Living in the Future


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Remote Video Lecture
Presented from Calit2 @ UCSD
CIAU Board of Visitors
Title: Living in the Future
La Jolla, CA

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  • Living in the Future

    1. 1. Living in the Future Remote Video Lecture CIAU Board of Visitors Presented from Calit2 @ UCSD June 18, 2007 Dr. Larry Smarr Director, California Institute for Telecommunications and Information Technology Harry E. Gruber Professor, Dept. of Computer Science and Engineering Jacobs School of Engineering, UCSD
    2. 2. Calit2 as an Experiment in the Future of Multi-Disciplinary Collaboration
    3. 3. California’s Institutes for Science and Innovation A Bold Experiment in Collaborative Research California NanoSystems Institute UCSF UCB California Institute for Bioengineering, Biotechnology, and Quantitative Biomedical Research California Institute for Telecommunications and Information Technology Center for Information Technology Research in the Interest of Society UCSC UCD UCM UCSB UCLA UCI UCSD
    4. 4. Calit2 Continues to Pursue Its Initial Mission: Envisioning How the Extension of Innovative Telecommunications and Information Technologies Throughout the Physical World will Transform Critical Applications Important to the California Economy and its Citizens’ Quality Of Life . Calit2 is a University of California “Institutional Innovation” Experiment on How to Invent a Persistent Collaborative Research and Education Environment that Provides Insight into How the UC, a Major Research University, Might Evolve in the Future . Calit2 Review Report: p.1
    5. 5. Where is Telecommunications Research Performed? A Historic Shift Source: Bob Lucky, Telcordia/SAIC U.S. Industry Non-U.S. Universities U.S. Universities Percent Of The Papers Published IEEE Transactions On Communications 70% 85%
    6. 6. Calit2--A Systems Approach to the Future of the Internet and its Transformation of Our Society Calit2 Has Assembled a Complex Social Network of Over 350 UC San Diego & UC Irvine Faculty Working in Multidisciplinary Teams With Staff, Students, Industry, and the Community Over 130 Companies and 300 Federal Grants in Collaboration with Calit2
    7. 7. Over the Next Decade Vast SensorNets Will Feed a Planetary Optical Core <ul><li>The Small </li></ul><ul><ul><li>Pervasive Self-Powered Micro- and Nano-Sensors </li></ul></ul><ul><li>The Cheap </li></ul><ul><ul><li>Mass Produced Radios </li></ul></ul><ul><li>The Smart </li></ul><ul><ul><li>System-on-Chip Integration of Computers with Sensors </li></ul></ul><ul><li>The Big </li></ul><ul><ul><li>Terabit Optical Internet Core </li></ul></ul><ul><ul><li>Gigabit Wireless Streams </li></ul></ul><ul><li>Calit2’s New Approach to Research </li></ul><ul><ul><li>Large Scale Testbeds </li></ul></ul><ul><ul><li>Build Integrated Systems </li></ul></ul><ul><ul><li>Work with End Users </li></ul></ul><ul><ul><li>Collaborate Across: </li></ul></ul><ul><ul><ul><li>Disciplines </li></ul></ul></ul><ul><ul><ul><li>Campuses </li></ul></ul></ul><ul><ul><ul><li>University / Industry </li></ul></ul></ul><ul><li>Calit2 Large Grant Examples: </li></ul><ul><ul><li>OptIPuter </li></ul></ul><ul><ul><li>CAMERA </li></ul></ul><ul><ul><li>LOOKING </li></ul></ul><ul><ul><li>RESCUE/WIISARD </li></ul></ul>Source: Rajesh Gupta, UCSD “ The all optical fibersphere in the center finds its complement in the wireless ethersphere on the edge of the network.” – George Gilder
    8. 8. Two New Calit2 Buildings Provide New Laboratories for “Living in the Future” <ul><li>“ Convergence” Laboratory Facilities </li></ul><ul><ul><li>Nanotech, BioMEMS, Chips, Radio, Photonics </li></ul></ul><ul><ul><li>Virtual Reality, Digital Cinema, HDTV, Gaming </li></ul></ul><ul><li>Over 1000 Researchers in Two Buildings </li></ul><ul><ul><li>Linked via Dedicated Optical Networks </li></ul></ul>UC Irvine Preparing for a World in Which Distance is Eliminated… UC San Diego
    9. 9. The Calit2@UCSD Building is Designed for Prototyping Extremely High Bandwidth Applications 1.8 Million Feet of Cat6 Ethernet Cabling 150 Fiber Strands to Building; Experimental Roof Radio Antenna Farm Ubiquitous WiFi Photo: Tim Beach, Calit2 Over 10,000 Individual 1 Gbps Drops in the Building ~10G per Person UCSD is Only UC Campus with 10G CENIC Connection for ~30,000 Users 24 Fiber Pairs to Each Lab
    10. 10. Calit2 StarCAVE Telepresence “Holodeck” 60 GB Texture Memory, Renders Images 3,200 Times the Speed of Single PC Source: Tom DeFanti, Greg Dawe, Calit2 Connected at 200 Gb/s
    11. 11. Collaborative Center for Internet Epidemiology and Defenses <ul><li>Joint project (UCSD/ICSI) </li></ul><ul><ul><li>One of Four National NSF CyberTrust Centers </li></ul></ul><ul><ul><li>~30 Participants (PIs, Staff, Students, etc) </li></ul></ul><ul><ul><li>~7M in Federal/State Funding : </li></ul></ul><ul><ul><ul><li>Microsoft, Intel, HP, VMWare, AT&T, Qualcomm </li></ul></ul></ul><ul><ul><ul><li>With Additional Support </li></ul></ul></ul><ul><li>Three Key Areas Of Interest </li></ul><ul><ul><li>Infrastructure and Analysis for Understanding Large-Scale Internet Threats </li></ul></ul><ul><ul><li>Automated Defensive Technologies </li></ul></ul><ul><ul><li>Forensic, Economic and Legal Issues </li></ul></ul><ul><li>Formed in November 2004 </li></ul>Source: Stefan Savage, CSE, UCSD Principal Investigators Stefan Savage , UCSD Vern Paxson , ICSI Co-Principal Investigators Alex Snoeren, UCSD George Varghese , UCSD Geoffrey M. Voelker , UCSD Nicholas Weaver , ICSI
    12. 12. UCSD Network Telescope <ul><li>Network Telescope: Monitor Large Range of Unused IP Addresses </li></ul><ul><ul><li>Will Receive Scans from Infected Hosts (or DDoS Backscatter) </li></ul></ul><ul><li>Very Scalable. </li></ul><ul><ul><li>UCSD Telescope Monitors 17M+ Addresses </li></ul></ul>Source: Stefan Savage, CSE, UCSD
    13. 13. Calit2 Brings Computer Scientists and Engineers Together with Biomedical Researchers <ul><li>Some Areas of Concentration: </li></ul><ul><ul><li>Algorithmic and System Biology </li></ul></ul><ul><ul><li>Bioinformatics </li></ul></ul><ul><ul><li>Metagenomics </li></ul></ul><ul><ul><li>Cancer Genomics </li></ul></ul><ul><ul><li>Human Genomic Variation and Disease </li></ul></ul><ul><ul><li>Proteomics </li></ul></ul><ul><ul><li>Mitochondrial Evolution </li></ul></ul><ul><ul><li>Computational Biology </li></ul></ul><ul><ul><li>Multi-Scale Cellular Imaging </li></ul></ul><ul><ul><li>Information Theory and Biological Systems </li></ul></ul><ul><ul><li>Telemedicine </li></ul></ul>UC Irvine UC Irvine Southern California Telemedicine Learning Center (TLC) National Biomedical Computation Resource an NIH supported resource center
    14. 14. Information Theorists Working with Bio, IT, and Nano Researchers Will Radically Transform Our View of Living Systems &quot;Through the strong loupe of information theory, we will be able to watch how such [living] beings do what nonliving systems cannot do: extract information from their surrounds, store it in a stable molecular form, and eventually parcel it out for their creative endeavors. ... So viewed, the information circle becomes the unit of life.” --Werner Loewenstein The Touchstone of Life (1999) Calit2’s Information Theory and Applications Center
    15. 15. Ericsson: A Calit2 Industrial Partner with Breadth and Depth <ul><li>Sponsored Research: Non-Exclusive Royalty Free </li></ul><ul><ul><li>$ 6.2 Million with UC Discovery Match </li></ul></ul><ul><ul><li>17 Professors, 17 Students, 4 Post-docs </li></ul></ul><ul><li>27 Student Fellowships </li></ul><ul><li>Two Endowed Chairs; Two Faculty Fellowships </li></ul><ul><li>Collaborations </li></ul><ul><ul><li>Magnus Almgren: Taught Course in ECE </li></ul></ul><ul><ul><li>Jaap Harsten, Bluetooth Hands-On Course </li></ul></ul><ul><li>Infrastructure </li></ul><ul><ul><li>Base Stations, Always Best Connected </li></ul></ul><ul><li>Help with </li></ul><ul><ul><li>New Federal Grants: $22.5 Million </li></ul></ul><ul><ul><li>Inspired Two Startups </li></ul></ul>Microlink Ericsson UCSD
    16. 16. Calit2 Has Developed Research Partnerships with California’s Major Trading Partners <ul><li>International Commerce Drives 25% Of California’s Economy </li></ul><ul><li>Largest Export Market is Computers and Electronic Products </li></ul><ul><li>Top Five Export Markets for California: </li></ul><ul><ul><li>Mexico </li></ul></ul><ul><ul><li>Japan </li></ul></ul><ul><ul><li>Canada </li></ul></ul><ul><ul><li>China </li></ul></ul><ul><ul><li>South Korea </li></ul></ul><ul><li>India is a Critical Growth Market for California </li></ul><ul><ul><li>California is the Top State Exporting to India </li></ul></ul><ul><ul><li>Exports Between California and India Increased ~30% from 2004 and 2005 </li></ul></ul><ul><li>India and US Have an Action Plan to Double Bilateral Trade in 3 Years </li></ul>i Grid 2005 Canada - California Strategic Innovation Partnership Summit
    17. 17. the Future of Ultra Broadband - Optical Networks, Massive Data Visualization, and Global Telepresence
    18. 18. Broadband Depends on Where You Are <ul><li>Mobile Broadband </li></ul><ul><ul><li>0.1-0.5 Mbps </li></ul></ul><ul><li>Home Broadband </li></ul><ul><ul><li>1-5 Mbps </li></ul></ul><ul><li>University Dorm Room Broadband </li></ul><ul><ul><li>10-100 Mbps </li></ul></ul><ul><li>Calit2 Global Broadband </li></ul><ul><ul><li>1,000-10,000 Mbps </li></ul></ul>100,000 Fold Range All Here Today! “ The future is already here, it’s just not evenly distributed” William Gibson, Author of Neuromancer
    19. 19. Dedicated Optical Channels Makes High Performance Cyberinfrastructure Possible Parallel Lambdas are Driving Optical Networking The Way Parallel Processors Drove 1990s Computing ( WDM) Source: Steve Wallach, Chiaro Networks “ Lambdas”
    20. 20. National Lambda Rail (NLR) and TeraGrid Provides Cyberinfrastructure Backbone for U.S. Researchers NLR 4 x 10Gb Lambdas Initially Capable of 40 x 10Gb wavelengths at Buildout Links Two Dozen State and Regional Optical Networks DOE, NSF, & NASA Using NLR San Francisco Pittsburgh Cleveland San Diego Los Angeles Portland Seattle Pensacola Baton Rouge Houston San Antonio Las Cruces / El Paso Phoenix New York City Washington, DC Raleigh Jacksonville Dallas Tulsa Atlanta Kansas City Denver Ogden/ Salt Lake City Boise Albuquerque UC-TeraGrid UIC/NW-Starlight Chicago International Collaborators NSF’s TeraGrid Has 4 x 10Gb Lambda Backbone
    21. 21. Lambda Services Enable 10Gb Line-Speed Security <ul><li>In the Real World, Users will Demand Secure Lambdas </li></ul><ul><li>They Require it to be Invisible and Add No Perceptible Latency </li></ul><ul><li>Nortel Prototype Demoed </li></ul><ul><li>AES-256 Encryption [e.g. NSA Approved for U.S. Top Secret] </li></ul><ul><li>Less than 500 nsecs Latency Added </li></ul><ul><li>Optical Multi-service Edge (OME) Switching Hardware </li></ul><ul><li>Used on Lightpaths from Amsterdam and Canada thru Starlight to San Diego </li></ul>Source: Kim RobertsNortel
    22. 22. <ul><li>September 26-30, 2005 </li></ul><ul><li>Calit2 @ University of California, San Diego </li></ul><ul><li>California Institute for Telecommunications and Information Technology </li></ul>Accelerator: Global Connections Between University Research Centers at 10Gbps T H E G L O B A L L A M B D A I N T E G R A T E D F A C I L I T Y Maxine Brown, Tom DeFanti, Co-Chairs 21 Countries Driving 50 Demonstrations 1 or 10Gbps to Calit2@UCSD Building Sept 2005 i Grid 2005
    23. 23. Building a Global Collaboratorium Sony Digital Cinema Projector 24 Channel Digital Sound Gigabit/sec Each Seat
    24. 24. Uncompressed HD Telepresence 1500 Mbits/sec Calit2 to UW Research Channel Over NLR Photo: Harry Ammons, SDSC John Delaney, PI LOOKING, Neptune May 23, 2007
    25. 25. First Trans-Pacific Super High Definition Telepresence Meeting in New Calit2 Digital Cinema Auditorium Lays Technical Basis for Global Digital Cinema Sony NTT SGI Streaming 4k with JPEG 2000 Compression ½ gigabit/sec Keio University President Anzai UCSD Chancellor Fox
    26. 26. The OptIPuter Project: Creating High Resolution Portals Over Dedicated Optical Channels to Global Science Data Picture Source: Mark Ellisman, David Lee, Jason Leigh Calit2 (UCSD, UCI) and UIC Lead Campuses—Larry Smarr PI Univ. Partners: SDSC, USC, SDSU, NW, TA&M, UvA, SARA, KISTI, AIST Industry: IBM, Sun, Telcordia, Chiaro, Calient, Glimmerglass, Lucent $13.5M Over Five Years
    27. 27. OptIPortal–Termination Device for the Dedicated Gigabit/sec Lightpaths Photo Source: David Lee, Mark Ellisman NCMIR, UCSD Scalable Adaptive Graphics Environment (SAGE) Integration of High Definition Video Streams with Large Scale Image Display Tiled Walls
    28. 28. My OptIPortal TM – Affordable Termination Device for the OptIPuter Global Backplane <ul><li>20 Dual CPU Nodes, 20 24” Monitors, ~$50,000 </li></ul><ul><li>1/4 Teraflop, 5 Terabyte Storage, 45 Mega Pixels--Nice PC! </li></ul><ul><li>Scalable Adaptive Graphics Environment ( SAGE) Jason Leigh, EVL-UIC </li></ul>Source: Phil Papadopoulos SDSC, Calit2
    29. 29. Beyond 4k – From 8 Megapixels Towards a Billion Megapixels Calit2@UCI Apple Tiled Display Wall Driven by 25 Dual-Processor G5s 50 Apple 30” Cinema Displays Source: Falko Kuester, Calit2@UCI NSF Infrastructure Grant Data—One Foot Resolution USGS Images of La Jolla, CA HDTV Digital Cameras Digital Cinema
    30. 30. High Resolution Aerial Photography Generates Images With 10,000 Times More Data than Landsat7 Shane DeGross, Telesis USGS Landsat7 Imagery 100 Foot Resolution Draped on elevation data New USGS Aerial Imagery At 1-Foot Resolution ~10x10 square miles of 350 US Cities 2.5 Billion Pixel Images Per City!
    31. 31. Multi-Gigapixel Images are Available from Film Scanners Today The Gigapxl Project Balboa Park, San Diego Multi-GigaPixel Image
    32. 32. Large Image with Enormous Detail Require Interactive LambdaVision Systems One Square Inch Shot From 100 Yards The OptIPuter Project is Pursuing Obtaining some of these Images for LambdaVision 100M Pixel Walls
    33. 33. The Future of Wireless Technology and Disaster Response
    34. 34. Transitioning to the “Always-On” Mobile Internet Cellular + WiFi
    35. 35. Network Endpoints Are Becoming Complex Systems-on-Chip <ul><li>Two Trends: </li></ul><ul><ul><li>More Use of Chips with “Embedded Intelligence” </li></ul></ul><ul><ul><li>Networking of These Chips </li></ul></ul>Source: Rajesh Gupta, UCSD Director, Center for Microsystems Engineering Calit2 Has Created Nano/ MEMS Clean Rooms, RF, Embedded Processor & System-on-Chip Labs
    36. 36. Calit2 CalRADIO Smart Radio Hardware/Software Teaching & Research Platform <ul><li>CalRADIO-I </li></ul><ul><ul><li>Digital Signaling Processor + ARM </li></ul></ul><ul><ul><li>Operating System </li></ul></ul><ul><ul><li>RF WiFi (802.11x) Chip Set </li></ul></ul><ul><ul><li>MAC Functionality into 'C' Code </li></ul></ul><ul><ul><li>A Test Instrument, An Access Point, And A WiFi Client </li></ul></ul><ul><li>CalRADIO-II </li></ul><ul><ul><li>Gather Requirements and Specifications </li></ul></ul><ul><ul><li>Layer 1 to Layer 7 Software Access </li></ul></ul><ul><ul><li>Several RF Front-End Modules </li></ul></ul><ul><ul><ul><li>802.11x </li></ul></ul></ul><ul><ul><ul><li>802.16 </li></ul></ul></ul><ul><ul><ul><li>Cell </li></ul></ul></ul><ul><ul><ul><li>General RF </li></ul></ul></ul>General Development Platform For Physical to Application Layers of Wireless Design Physical layer Link layer Network layer Transport Session layer Presentation Application
    37. 37. The CWC Provides Calit2 With Deep Research in Many Component Areas Two Dozen ECE and CSE Faculty LOW-POWERED CIRCUITRY ANTENNAS AND PROPAGATION COMMUNICATION THEORY COMMUNICATION NETWORKS MULTIMEDIA APPLICATIONS RF Mixed A/D ASIC Materials Smart Antennas Adaptive Arrays Modulation Channel Coding Multiple Access Compression Architecture Media Access Scheduling End-to-End QoS Hand-Off Scalable Video Smart Spaces Speech Recognition Center for Wireless Communications Source: UCSD CWC
    38. 38. Calit2 Has Extensive Circuits and Systems Labs <ul><li>Millimeter Wave Lab: </li></ul><ul><ul><li>20mHz–110GHz, uProbe Stations </li></ul></ul><ul><ul><li>Low Noise Shield Room </li></ul></ul><ul><ul><li>Micro-Amps & Micro-Meters </li></ul></ul><ul><li>Power Lab Testbeds: </li></ul><ul><ul><li>200mW – 2000W Amplifiers </li></ul></ul><ul><ul><li>Battery Management </li></ul></ul><ul><li>Assembly and Wet Etch Lab </li></ul><ul><li>Wireless Platforms Lab: </li></ul><ul><ul><li>DSP & FPGA Development Tools </li></ul></ul><ul><ul><li>System Integration </li></ul></ul><ul><ul><li>Interoperability Testbed </li></ul></ul><ul><li>Basestation Lab: </li></ul><ul><ul><li>Rooftop, On-the-Air Cellular Lab and Experimental Licenses </li></ul></ul>
    39. 39. The Center for Pervasive Communications and Computing Will Have a Major Presence in the Calit2@UCI Building Director Ender Ayanoglu
    40. 40. Research on Res ponding to C rises and U nexpected E vents (RESCUE) Information Flow Within the Responding Organizations and the Public PIs: Sharad Mehrotra, UCI; Ramesh Rao, UCSD Five-Year $12.5 Million Large ITR Award-Started Oct 1, 2003 <ul><li>Networking & Computing Systems </li></ul><ul><ul><li>Computing, Communication, & Storage Systems Under Extreme Situations </li></ul></ul>Information Centric Computing Enhanced Situational Awareness Social & Disaster Science Context, Model & Understanding of Process, Organizational Structure, Needs Engineering & Transportation Validation Platform for Role of IT Research <ul><li>Security, Privacy& Trust </li></ul><ul><li>Cross Cutting Issue at Every Level </li></ul>
    41. 41. RESCUE Community Advisory Board Ellis Stanley – Chair General Manager, City of Los Angeles Emergency Preparedness Department Karen Butler Program Manager Communications Division San Diego Police Department William Maheu Assistant Chief of Police City of San Diego David Rose Lieutenant Officer UC San Diego Police Department Linda Bogue Emergency Mgmt. Coordinator Environmental Health and Safety University of California, Irvine Jim Watkins (retired) Governor’s Office Emergency Services Bob Garrott Los Angeles County Office of Emergency Mgmt. Paulette Murphy Space and Naval Warfare Systems Command (SPAWAR) Dawna Finley Tom Hume Eileen Salmon City of Irvine Emergency Management
    42. 42. Desired Features Wireless Network Reconstruction <ul><li>Quick Deployment at Ground Zero </li></ul><ul><li>Low Cost of Deployment and Ability to Use the Available Local Network Services </li></ul><ul><li>Minimal Configuration and Setup Complexity (Minimal Network Planning Time) </li></ul><ul><li>Flexibility in Network Reconfiguration </li></ul><ul><li>High Reliability, Availability, and Fault Tolerance </li></ul><ul><li>The Preferred Choice is a Hybrid Wireless Mesh Network </li></ul>
    43. 43. Calit2’s CalMesh— Re-establishing Internet Access & Team Communication <ul><li>Self-Organizing--Forms a Reliable Wireless Mesh Network  </li></ul><ul><li>Creates a Local “Wireless Bubble” 802.11-based WiFi </li></ul><ul><li>Variety of Backhaul Communication Technologies to Connect to Internet </li></ul><ul><ul><li>Ethernet, </li></ul></ul><ul><ul><li>1xEVDO, 1xRTT, </li></ul></ul><ul><ul><li>WCDMA, UMTS, </li></ul></ul><ul><ul><li>WiMax   </li></ul></ul><ul><li>Supports Data and VoIP-Based Voice Traffic </li></ul>
    44. 44. NSF-Funded ResponSphere Establishes Calit2 Project Rescue Testbeds in Irvine and in San Diego <ul><li>Gaslamp Quarter , San Diego/UCSD </li></ul><ul><ul><li>Ubiquitous Wireless Coverage in Downtown San Diego </li></ul></ul><ul><ul><li>Test Network Architecture Enhancement and New Applications </li></ul></ul><ul><li>Crisis Assessment, Mitigation, And Analysis – UCI Campus </li></ul><ul><ul><li>Field-Test and Refine Research on Information Collection, Analysis, Sharing, and Dissemination in Controlled yet Realistic Settings </li></ul></ul>
    45. 45. NSF RESCUE Strongly Coupled with NIH WIISARD Grant W ireless I nternet I nformation S ystem for Medic a l R esponse in D isasters First Tier Mid Tier Wireless Networks Triage Command Center Reality Flythrough Mobile Video 802.11 pulse ox Calit2 is Working Closely with the First Responder Community
    46. 46. Calit2 Has Introduced Innovative Wireless Systems to Support SoCal First Responders <ul><li>Aug. 22, 2006 MMST </li></ul><ul><li>Disaster Drill at </li></ul><ul><li>Calit2@UCSD Involved </li></ul><ul><li>Over 200 First Responders </li></ul>
    47. 47. Translating Field Experience Through the National Research Council’s CSTB
    48. 48. The Future of Nanobioinfo Convergence
    49. 49. President Kalam of India Believes Nanobioinfotech is the Future for 600,000 Villages <ul><li>Interactive Knowledge System </li></ul><ul><li>Convergence of Info- Nano - Bio </li></ul><ul><li>Make the Bandwidth Available with No Limits </li></ul><ul><li>PURA--Societal Grid With Electronic Connection of a Billion People </li></ul>Photo: Alan Decker, UCSD
    50. 50. Enormous Increase in Scale of Known Genes Over Last Decade 6.3 Billion Bases 5.6 Million Genes 1.8 Million Bases 1749 Genes ~3300x 1995 First Microbe Genome 2007 Ocean Microbial Metagenomics
    51. 51. Marine Genome Sequencing Project – Measuring the Genetic Diversity of Ocean Microbes Sorcerer II Data Will Double Number of Proteins in GenBank! Plus 155 Marine Microbial Genomes Specify Ocean Data Each Sample ~2000 Microbial Species
    52. 52. PI Larry Smarr Paul Gilna Ex. Dir. Calit2 is Now Attracting Private Foundation Grants Announced January 17, 2006--$24.5M Over Seven Years
    53. 53. Calit2’s Direct Access Core Architecture Will Create Next Generation Metagenomics Server Traditional User Response Request Source: Phil Papadopoulos, SDSC, Calit2 + Web Services <ul><ul><li>Sargasso Sea Data </li></ul></ul><ul><ul><li>Sorcerer II Expedition (GOS) </li></ul></ul><ul><ul><li>JGI Community Sequencing Project </li></ul></ul><ul><ul><li>Moore Marine Microbial Project </li></ul></ul><ul><ul><li>NASA Goddard Satellite Data </li></ul></ul><ul><ul><li>Community Microbial Metagenomics Data </li></ul></ul>Flat File Server Farm W E B PORTAL Dedicated Compute Farm (100s of CPUs) TeraGrid: Cyberinfrastructure Backplane (scheduled activities, e.g. all by all comparison) (10000s of CPUs) Web (other service) Local Cluster Local Environment Direct Access Lambda Cnxns Data- Base Farm 10 GigE Fabric
    54. 54. Calit2 is Now OptIPuter Connecting Remote Moore-Funded Microbial Researchers NW! CICESE UW JCVI MIT SIO UCSD SDSU UIC EVL UCI OptIPortals OptIPortal UC Davis
    55. 55. Distribution of CAMERA User Registrations Nearly 1000 Registered Users From 45 Countries
    56. 56. Accelerator: The Perfect Storm-- Convergence of Engineering with Bio, Physics, & IT 2 mm HP MemorySpot Nanobio info technology 1000x Magnification MEMS 2 micron DNA-Conjugated Microbeads Human Adenovirus 400x Magnification NANO IBM Quantum Corral Iron Atoms on Copper 5 nanometers 400,000 x !
    57. 57. Calit2 is Creating a Nano-Bio-Info Innovation Laboratory at UC Irvine Donald Bren School of Information and Computer Science
    58. 58. Start with Fabrication Facilities for Micro & Nanosystems 8600 SQ FT clean room space with class 100/1000/10000 areas SEM/EDX with 3 nm resolution on 100 mm wafers Double-sided mask aligner for 150 mm wafers Low-temp PECVD Founded 1999 E-beam Lithography 40 UCI Faculty from a Dozen Departments; 75 Industrial Users Deep Reactive Ion Etcher for bulk micromachining
    59. 59. INRF Supports Researchers in Nano and BioMEMS BioMEMS and Medical Applications Nanotechnology / Nanofabrication Spray atomization of nano powders New methods of making arrays of nanowires Boron-based nanowires for novel circuits Carbon nanotubes for sensor and electronic applications Micromirror on a catheter for optical biopsy using coherence tomography Protein crystallization in nanovolumes 0 ms 200 ms 400 ms 600 ms Microfluidic devices for electrophoretic separations Microfluidic devices using droplets, CD microfluidics and magnetohydrodynamics
    60. 60. INRF Also Supports Development of Novel Photonics and RF Devices Fiberoptic Communications RF and Wireless Communications Micro mirrors and tunable Fabry-Perot Interferometers Polymer waveguides, polarization controllers and other electro-optical devices Intelligent fiber-optic alignment algorithms All-fiber tunable devices including acousto-optic tunable filters Microwave imaging for damage assessment of structures Reconfigurable antennas with integrated RF MEMS switches Fe-GaAs integrated wideband microwave devices MEMS-based ultra-low-power RF receivers High-speed RF mixed-signal circuit design LNA Mechanical Mixer-Filter Mechanical RF Channel Selector Mechanical Switchable Resonator Vc
    61. 61. Example: Real-Time Electronic Readout from Single Biomolecule Sensors <ul><li>Carbon Nanotube Circuits Provide Nanoscale Connectivity </li></ul><ul><li>New Techniques Integrate Single-Molecule Attachments </li></ul><ul><li>Dynamics and Interactions With the Environment Can be Directly Measured </li></ul><ul><li>Electronic Readout Compatible With Hand-held, Low-power Devices </li></ul>Source: Phil Collins & Greg Weiss, Calit2@UCI 1 nm wiring 1 protein molecule … and without device in buffer with reagents Schematic & SEM Image of Carbon Nanotube-based Device
    62. 62. Add in New Nanofabrication and Material Characterization Labs at Calit2@UCI <ul><li>Zeiss Microscopy Center </li></ul><ul><ul><li>Focused Ion Beam </li></ul></ul><ul><ul><li>FEG-SEM </li></ul></ul><ul><ul><li>Environmental SEM </li></ul></ul><ul><li>Thermal Analysis Lab and Atomic Force Microscope </li></ul><ul><li>Nanoimprinting Facility </li></ul>Zeiss FIB 1-nm Carbon Nanotube Imaged by AFM Nanoimprinter
    63. 63. Calit2@UCI Nanobioinfotechnology “Innovation Pipeline” INRF Calit2 BiON Zeiss Center of Excellence Micro/Nano Materials and Devices Bio-Organic Nano Lab SEM, Advanced Characterization Three centers share a common infrastructure Photonics, RF, Chip Labs Integrate with Chips, Telecom Source: GP Li, Calit2
    64. 64. Lifechips--Merging Two Major Industries: Microelectronic Chips & Life Sciences LifeChips: the merging of two major industries, the microelectronic chip industry with the life science industry LifeChips medical devices 65 UCI Faculty
    65. 65. Calit2 Materials and Devices Laboratory: “Nano3” – Science, Engineering, Medicine Nano3 Facility CALIT2.UCSD 10,000 sq. feet Materials and Devices Labs Class 100/1000 Nearly 50 Academic Projects Source: Bernd Fruhberger, Calit2
    66. 66. Nano-Structured Porous Silicon Applied to Cancer Treatment Michael J. Sailor Research Group Chemistry and Biochemistry Nanostructured “Mother Ships” for Delivery of Cancer Therapeutics Nanodevices for In-vivo Detection & Treatment of Cancerous Tumors
    67. 67. A World of Distributed Sensors Starts with Integrated Nanosensors Ivan Schuller holding the first prototype in 2004 I. K. Schuller, A. Kummel, M. Sailor, W. Trogler, Y-H Lo Developing Multiple Nanosensors on a Single Chip, Integrated with Local Processing and Wireless Communications Technology Transfer: RedX (Explosive Sensors), RheVision (Fauvation Optics) 2006 MURI for Nanostructured Supersensors Guided wave optics Aqueous bio/chem sensors Fluidic circuit Free space optics Physical sensors Gas/chemical sensors Electronics (communication, powering)
    68. 68. Two Companies Spun Off From UCSD MURI for Nanostructured Supersensors <ul><li>Red X Defense – Innovative Security Solutions </li></ul>X PAK X Pro Kiosk High-Throughput Hand Screening for Explosives Explosives Detection on Surfaces FIRST PRODUCTS SHIP FEBRUARY, 2007