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CRI/Criterion has deployed high-throughput tools for formulation of new catalyst compositions, and for testing the performance of the catalysts in several applications. This ability allows for screening of a large number of catalysts in a very short amount of time, significantly reducing the time required for catalyst development. The high-throughput screening ability has been proven in several areas of CRI/Criterion’s businesses, including chemicals and refining. High-throughput screening tools are equally, if not more, valuable in speedy deployment of biofuels and biochemicals from the lab to the market. Here we provide an overview of a program for rapid catalyst and process development to convert a mixed alcohol feed into gasoline and kerosene range hydrocarbons.