PharmaceuticalManagement for theControl of Malaria in           Pregnancy                       Rima Shretta              ...
Background: IPTp• By 2010, 37 countries had adopted IPTp (WMR, 2011)• SP for IPTp is free for pregnant women and available...
Background: Insecticide Treated Nets• A total of 82 countries, of which 38 are in the African Region,  distribute ITNs fre...
Background: Treatment• 11 of 13 countries surveyed in 2007-8, fewer than 15% of  children received an ACT. WMR (2011) esti...
Challenges• Availability of SP: 0-100% (PMI)• Frequent and long stock-outs of SP. Data from PMI:   • Stock outs greater th...
Challenges• PMI (2009-2011)   • ACT stock outs: Up to 90% in some countries   • Quinine stock outs: > 60% (tabs); Up to 63...
Countries Reporting Stock Outs of SP at Central Level                      25                                             ...
Countries Reporting Stockouts ofArtemether/Lumefantrine Products at Central Level                        18               ...
Percent of Facilities Stocked Out of SP on Day of Visit:One Country Example100%90%80%70%60%50%40%30%20%10% 0%         Qtr ...
Zambia: Case Study• In 2008, 50.3% of pregnant women reported sleeping  under a mosquito net the previous night and 43.2% ...
Zambia: Case Study• A 2008 assessment by HSSP in Central and Eastern  provinces found that of 54 facilities surveyed, 95% ...
Improving access to Malaria in Pregnancy Strategies by  Pharmaceutical Management and Health Systems                    St...
Selection and Policy      Selection and          Policy• Lack of clarity in policy guidelines causing uncertainty  among h...
Quantification and Procurement  Quantification      and  Procurement• Poor quantification• Lack of procurement plan – unco...
Storage and Distribution    Storage, Distri    bution and    Inventory    Management•   Poor storage capacity: LLINs•   Po...
Prescribing, Dispensing and Use     Prescribing, Di     spensing and        Patient       Adherence• Use of SP for treatme...
Recommended Pharmaceutical ManagementIntereventions• Clear guidelines emphasizing efficacy (even in areas with 25%  SP tre...
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Malaria in Pregnancy-Strengthening Health Systems to Improve Outcomes for MIP_Shretta_5.2.12

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Malaria in Pregnancy-Strengthening Health Systems to Improve Outcomes for MIP_Shretta_5.2.12

  1. 1. PharmaceuticalManagement for theControl of Malaria in Pregnancy Rima Shretta May 2, 2012 CORE meeting, Wilmington, Delaware
  2. 2. Background: IPTp• By 2010, 37 countries had adopted IPTp (WMR, 2011)• SP for IPTp is free for pregnant women and available at health facilities during ANC• Household survey data from 13 African countries 2008–2010 indicated that women who received two doses of IPTp during pregnancy in ranged from 4% in Namibia to 68% in Zambia (average: 24%)• Data on IPTp coverage from national surveys remains limited
  3. 3. Background: Insecticide Treated Nets• A total of 82 countries, of which 38 are in the African Region, distribute ITNs free of charge to for all persons at risk for malaria in accordance with WHO recommendations• Mass distribution was the primary channel of distribution in followed by distribution through antenatal clinics• Proportion of households owning at least one ITN in sub- Saharan Africa has risen from 3% in 2000 to 50% in 2011• Despite the investment in LLIN distribution, global coverage still below the 80% target set by RBM and 85% by PMI
  4. 4. Background: Treatment• 11 of 13 countries surveyed in 2007-8, fewer than 15% of children received an ACT. WMR (2011) estimates that about 65% of treatment needs are fulfilled for patients attending public health facilities (children)• Limited data available for pregnant women for ACTs and quinine• Coverage still below the 80% target set by RBM and 85% by PMI• Anectdotal data: high percentage of quinine use for uncomplicated malaria in children and non-pregnant adults
  5. 5. Challenges• Availability of SP: 0-100% (PMI)• Frequent and long stock-outs of SP. Data from PMI: • Stock outs greater than 3 days: SP: 0-37.5% facilities ITNs: upto 47% RDTs: upto 46%• Number of days of stock outs of SP vary from a 16 days (data from PMI countries) to four months (MCHIP, 2011)• Availability of LLINs: inadequate distribution of LLINs particularly at ANC level• Use of SP for treatment: 1-25% health facilities (PMI)
  6. 6. Challenges• PMI (2009-2011) • ACT stock outs: Up to 90% in some countries • Quinine stock outs: > 60% (tabs); Up to 63% (inj)• Poor inventory management • Facilities with up to date stock cards: 27-78%• Training • Providers with in-service training in IPTp: 36-96% • Providers with in-service training in SM: 36-100%• Poor distribution • Difference between products ordered vs. received: 64%
  7. 7. Countries Reporting Stock Outs of SP at Central Level 25 20 20 19 19 17Number of Countries 15 14 13 SP Stockout 10 10 8 7 Total Countries 6 6 Reporting SP Products 5 5 0 Qtr 1 Qtr 2 Qtr 3 Qtr 4 Qtr 1 Qtr 2 Qtr 3 Qtr 4 Source: USAID|DELIVER Project. 2012. Procurement Planning & Monitoring Report – Malaria. Note: Quarters 2, 3, and 4 of 2011 include 6, 8, and 7 Nigerian states, respectively, reporting independently.
  8. 8. Countries Reporting Stockouts ofArtemether/Lumefantrine Products at Central Level 18 16 14 A/L 6x1 Stockout 12 Number of Countries A/L 6X2 Stockout 10 8 A/L 6x3 Stockout 6 A/L 6x4 Stockout 4 Total Countries Reporting A/L 2 Products 0 Qtr 3 Qtr 4 Qtr 1 Qtr 2 Qtr 3 Qtr 4 Qtr 1 Qtr 2 Qtr 3 Qtr 4 Qtr 1 Qtr 2 2008 2009 2010 2011 Source: USAID|DELIVER Project. 2011. Procurement Planning & Monitoring Report – Malaria.
  9. 9. Percent of Facilities Stocked Out of SP on Day of Visit:One Country Example100%90%80%70%60%50%40%30%20%10% 0% Qtr 1 Qtr 2 Qtr 3 Qtr 4 Qtr 1 Qtr 2 Qtr 3 Qtr 4 Qtr 1 Qtr 2 Qtr 3 Qtr 4 Qtr 1 2009 2010 2011 2012 Source: USAID|DELIVER Project. 2012. PMI End Use Verification Activity. Data provide a snapshot of commodity availability and are not nationally representative.
  10. 10. Zambia: Case Study• In 2008, 50.3% of pregnant women reported sleeping under a mosquito net the previous night and 43.2% reported sleeping under a treated net• SP is stocked out much of the time in health facilities and at the central level and ITNs are available in health facilities only periodically• Misuse of SP for case management• Procurement and distribution not efficient• Responsibilities of the NMCC and Pharmacy Unit in addressing stockouts not clearly defined Source: MCHIP, 2010
  11. 11. Zambia: Case Study• A 2008 assessment by HSSP in Central and Eastern provinces found that of 54 facilities surveyed, 95% had experienced a stock-out of SP in the period of July 2007 to July 2008• No procurement plan in place-procurement according to funding level available• Lack of accurate consumption data from health facilities challenging quantification• Delays in the receipt of donor funds Source: MCHIP, 2010
  12. 12. Improving access to Malaria in Pregnancy Strategies by Pharmaceutical Management and Health Systems Strengthening • Long lasting • Safe motherhood insecticide- and f-ANC treated nets strategies (LLINs) including Governance detection and treatment of anemia Quantification and Selection and Policy Procurement Service Delivery Human Resources Access Storage, Distribution Prescribing, Dispensing and Inventory and Patient Adherence Management Financing Information • Intermittent • Diagnosis and preventive treatment with treatment of ACTs/quinine pregnant women (IPTp)
  13. 13. Selection and Policy Selection and Policy• Lack of clarity in policy guidelines causing uncertainty among health workers including timing of doses• Suspicion in promoting SP for IPTp, but using ACTs for treatment• Free vs. payment for products
  14. 14. Quantification and Procurement Quantification and Procurement• Poor quantification• Lack of procurement plan – uncoordinated procurement• Lack of consumption and burden data• Problems with management of stocks at all levels
  15. 15. Storage and Distribution Storage, Distri bution and Inventory Management• Poor storage capacity: LLINs• Poor distribution to peripheral areas• Transport• Poor reporting systems and inventory management
  16. 16. Prescribing, Dispensing and Use Prescribing, Di spensing and Patient Adherence• Use of SP for treatment – stock outs and resistance development• Lack of water and cups for administering DOT• Concerns about administering SP late in pregnancy• In-service training and supervision
  17. 17. Recommended Pharmaceutical ManagementIntereventions• Clear guidelines emphasizing efficacy (even in areas with 25% SP treatment failures, IPTp with SP provides benefits to pregnant women)• Financing• Procurement planning• Forecasting• Distribution plans/microplanning• IEC/BCC• Training in case and supply chain management and IPTp• Strengthen routine distribution of nets through ANC• Strengthen monitoring and data reporting on IPTp as well as treatments given during pregnancy

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