View stunning SlideShares in full-screen with the new iOS app!Introducing SlideShare for AndroidExplore all your favorite topics in the SlideShare appGet the SlideShare app to Save for Later — even offline
View stunning SlideShares in full-screen with the new Android app!View stunning SlideShares in full-screen with the new iOS app!
IN VITRO EVALUATION THE CITREX® MOLECULE INHIBITORY/CIDAL ACTIVITY AGAINST DIFFERENT ORGANISMS HAROLD EDUARDO DURANGO G. Medical Mycology Bacteriologist Professor of Microbiology and Parasitology. Medicine Faculty, U. of A. JOSE IGNACIO BARGUIL P. Food Microbiology Bacteriologist Food protection technical consultant, Consultant for Banco Interamericano de Desarrollo, BID. Technical Director, Continua Consultores. Pediatric Infectology Research Laboratory. H.U.S.V.P
Result summary from all 3 tests * Corresponds to MIC in 2 of 3 tests 50 A. flavus 12.5 – 25* C. albicans 12.5 – 25* E. faecalis 12.5 S. aureus 200 V. cholerae 200 S. typhimurium 200 E. coli 800 P. aeruginosa Minimum Inhibitory Concentration (ppm CITREX ®) Microorganism
MBC’s are more useful to follow up drug’s microbicidal activity in patients under specific antibiotic therapy. Even though it can be useful if taken into account at the time of choosing a product for the control of specific processes.
MBC is determined by culture in a gel medium from the 4 tubes with the highest test drug, from the tube representing the Minimum Inhibitory Concentration.
CITREX ® Liquid Minimal Bactericidal Concentration 200 A. flavus 50 C. albicans 50 E. faecalis 25 S. aureus 400 V. cholerae 400 S. typhimurium 800 E. coli 1000 P. aeruginosa Minimum Bactericidal Concentration (ppm) Microorganism
Variation in one concentration in the case of Enterococcus faecalis and Candida albicans , is probably due to the inoculum effect (a drift in the standardization of bacterial suspension, when compared with McFarland’s turbidity pattern).
Therefore, result summary table shows a MIC range for these organisms in bold (*); i.e. the result from 2 of the 3 assays performed .