Dr. Brian J. Spiering
email: bspiering@gmail.com
website: brianspiering.com
5 fMRI Research Wins
5 fMRI Research Wins
1) Have a Theory
2) Build a Behavioral Base
3) Design, Redesign
4) Create an Analysis Hitlist
5) Make...
1) Have a Theory
A theory can be proved by experiment;
but no path leads from experiment
to the birth of a theory.
- Manfr...
- Begin with the neuroanatomy
- Account for previous results
- Make specific, falsifiable predictions
1) Have a Theory
Ashby et al. (1998)
Ashby, Paul, & Maddox (2011)
COVIS
(Competition BetweenVerbal and Implicit Systems)
SPEED
(Subcortical Pathways Enable Expertise Development)
Ashby, Ennis, & Spiering (2007)
Pessoa & Adolphs (2011)
Pessoa (2011)
Pessoa (2011)
2) Build a Behavioral Base
All life is an experiment.
The more experiments you make the better.
- Ralph Waldo Emerson
2) Build a Behavioral Base
- Understand the literature
- Pick the low hanging fruit
- Simplify, simplify, simplify
Category Learning Task
Category Learning Stimuli
Unstructured Categorization
Rule-Based Categorization
Information-Integration Categorization
Experiment 1 - Within
Experiment 1 - Within
Training Accuracy
Experiment 1 - Within
Transfer Accuracy
Experiment 2 - Between
Experiment 2 - Between
Training Accuracy
Experiment 2 - Between
Transfer Accuracy
3) Design, Redesign
Design is not just what it looks like.
Design is how it works.
- Steve Jobs
3) Design, Redesign
- Define project outcome
- Thrash Now
- Create a devil’s advocate
fMRI Methods
Results
Results
Results
ResultsResults
4) Create an Analysis Hitlist
It's not the plan that is important,
it's the planning.
- Dr. Graeme Edwards
4) Create an Analysis Hitlist
- Door wide open
- Think through all steps
- 2 week sprints
Expectancy violation in
cadence perception
Standard Ending
Deceptive Ending
Modulation Ending
Atonal Ending
Music-related Activations
Music > Silence Baseline
Ending-related Activations
All Ending > Music Baseline
Cortex Activation by Ending
Anatomical ROIs
Standard Ending - .01
Deceptive Ending - .02
Modulation Ending - .05
Atonal Ending - .99
Parametric Regressor
Basal Ganglia
Parametric Activation
Granger Causality Modeling
5) Make Writing Fast (& Fun)
The faster I write the better my output.
If I’m going slow I’m in trouble.
It means I’m pushi...
Analysis Paper
Door Open Door Closed
Team Single Advocate
Compile Winnow
Smith,Ashby, Berg, Murphy, Spiering, Cook, & Grace, 2011
F. Greg Ashby Carol A. Seger
Erik J. Peterson
Dan Lopez-Paniagua
Kurt Braunlich
Anastasia Sares
Alexander Gonzalez
Catie A...
fMRI (functional magnetic resonance imaging) research wins
fMRI (functional magnetic resonance imaging) research wins
fMRI (functional magnetic resonance imaging) research wins
fMRI (functional magnetic resonance imaging) research wins
fMRI (functional magnetic resonance imaging) research wins
fMRI (functional magnetic resonance imaging) research wins
fMRI (functional magnetic resonance imaging) research wins
fMRI (functional magnetic resonance imaging) research wins
fMRI (functional magnetic resonance imaging) research wins
Upcoming SlideShare
Loading in …5
×

fMRI (functional magnetic resonance imaging) research wins

863 views

Published on

Best practices for neuroimaging.

Published in: Health & Medicine, Technology
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
863
On SlideShare
0
From Embeds
0
Number of Embeds
38
Actions
Shares
0
Downloads
36
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

fMRI (functional magnetic resonance imaging) research wins

  1. 1. Dr. Brian J. Spiering email: bspiering@gmail.com website: brianspiering.com 5 fMRI Research Wins
  2. 2. 5 fMRI Research Wins 1) Have a Theory 2) Build a Behavioral Base 3) Design, Redesign 4) Create an Analysis Hitlist 5) Make Writing Fast (& Fun)
  3. 3. 1) Have a Theory A theory can be proved by experiment; but no path leads from experiment to the birth of a theory. - Manfred Eigen
  4. 4. - Begin with the neuroanatomy - Account for previous results - Make specific, falsifiable predictions 1) Have a Theory
  5. 5. Ashby et al. (1998) Ashby, Paul, & Maddox (2011) COVIS (Competition BetweenVerbal and Implicit Systems)
  6. 6. SPEED (Subcortical Pathways Enable Expertise Development) Ashby, Ennis, & Spiering (2007)
  7. 7. Pessoa & Adolphs (2011)
  8. 8. Pessoa (2011)
  9. 9. Pessoa (2011)
  10. 10. 2) Build a Behavioral Base All life is an experiment. The more experiments you make the better. - Ralph Waldo Emerson
  11. 11. 2) Build a Behavioral Base - Understand the literature - Pick the low hanging fruit - Simplify, simplify, simplify
  12. 12. Category Learning Task
  13. 13. Category Learning Stimuli
  14. 14. Unstructured Categorization
  15. 15. Rule-Based Categorization
  16. 16. Information-Integration Categorization
  17. 17. Experiment 1 - Within
  18. 18. Experiment 1 - Within Training Accuracy
  19. 19. Experiment 1 - Within Transfer Accuracy
  20. 20. Experiment 2 - Between
  21. 21. Experiment 2 - Between Training Accuracy
  22. 22. Experiment 2 - Between Transfer Accuracy
  23. 23. 3) Design, Redesign Design is not just what it looks like. Design is how it works. - Steve Jobs
  24. 24. 3) Design, Redesign - Define project outcome - Thrash Now - Create a devil’s advocate
  25. 25. fMRI Methods
  26. 26. Results
  27. 27. Results
  28. 28. Results
  29. 29. ResultsResults
  30. 30. 4) Create an Analysis Hitlist It's not the plan that is important, it's the planning. - Dr. Graeme Edwards
  31. 31. 4) Create an Analysis Hitlist - Door wide open - Think through all steps - 2 week sprints
  32. 32. Expectancy violation in cadence perception
  33. 33. Standard Ending
  34. 34. Deceptive Ending
  35. 35. Modulation Ending
  36. 36. Atonal Ending
  37. 37. Music-related Activations Music > Silence Baseline
  38. 38. Ending-related Activations All Ending > Music Baseline
  39. 39. Cortex Activation by Ending
  40. 40. Anatomical ROIs
  41. 41. Standard Ending - .01 Deceptive Ending - .02 Modulation Ending - .05 Atonal Ending - .99 Parametric Regressor
  42. 42. Basal Ganglia Parametric Activation
  43. 43. Granger Causality Modeling
  44. 44. 5) Make Writing Fast (& Fun) The faster I write the better my output. If I’m going slow I’m in trouble. It means I’m pushing the words instead of being pulled by them. -Raymond Chandler
  45. 45. Analysis Paper Door Open Door Closed Team Single Advocate Compile Winnow
  46. 46. Smith,Ashby, Berg, Murphy, Spiering, Cook, & Grace, 2011
  47. 47. F. Greg Ashby Carol A. Seger Erik J. Peterson Dan Lopez-Paniagua Kurt Braunlich Anastasia Sares Alexander Gonzalez Catie Alpeter Sarah Quraini Collaborators

×