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Acute Coronary Syndrome
 

Acute Coronary Syndrome

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The presentation explore the facts of Coronary Syndrome and its complications.

The presentation explore the facts of Coronary Syndrome and its complications.

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  • Note: Plavix® (clopidogrel bisulfate) is not indicated for all the conditions listed on this slide. <br /> Vascular disease is the common underlying disease process for MI, ischemia and vascular death. <br /> Acute coronary syndrome (ACS) is a classic example of the progression of vascular disease to an ischemic event. <br /> ACS (in common with ischemic stroke and critical leg ischemia) is typically caused by rupture or erosion of an atherosclerotic plaque followed by formation of a platelet-rich thrombus. <br /> Atherosclerosis is an ongoing process affecting mainly large and medium-sized arteries, which can begin in childhood and progress throughout a person’s lifetime. <br /> Stable atherosclerotic plaques may encroach on the lumen of the artery and cause chronic ischemia, resulting in (stable) angina pectoris or intermittent claudication, depending on the vascular bed affected. <br /> Unstable atherosclerotic plaques may rupture, leading to the formation of a platelet-rich thrombus that partially or completely occludes the artery and causes acute ischemic symptoms. <br />
  • Platelets are recognized to play an integral role in acute coronary syndromes and arterial thrombosis. After plaque fissure or rupture, there is platelet adhesion and activation. This leads to platelet aggregation within the coronary artery, and ultimately partial or complete occlusion of the coronary artery. <br />

Acute Coronary Syndrome Acute Coronary Syndrome Presentation Transcript