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Diabetes and Cardiovascular Risk in Driftpile First Nation: Longitudinal Results

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2010 (Oct) Canadian Diabetes Association Conference, poster presentation by BRAID Research

2010 (Oct) Canadian Diabetes Association Conference, poster presentation by BRAID Research

Published in: Health & Medicine
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  • 1. Diabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDriftpile First Nation: Longitudinal ResultsDriftpile First Nation: Longitudinal ResultsKelli RalphKelli Ralph--Campbell, Richard T. Oster, Ellen L. Toth, BRAID Diabetes ResearCampbell, Richard T. Oster, Ellen L. Toth, BRAID Diabetes Research Group, University of Alberta, Edmonton, AB;ch Group, University of Alberta, Edmonton, AB;Florence Willier, Paulette Campiou, Trina Scott, Driftpile FirstFlorence Willier, Paulette Campiou, Trina Scott, Driftpile First Nation, ABNation, ABAbstractThe longitudinal BRAID1 study has been ongoing in Driftpile FirstNation since 2003. Approximately 52% of the population residing inDriftpile (Canada Census, 2006) has been screened for diabetesand cardiovascular risk, of whom 34% returned for at least onefollow-up visit. Our purpose was to examine, longitudinally,diabetes-related risk factors among returning individuals.Clinical and anthropometric measurements (blood glucose,hemoglobin A1c, cholesterol, blood pressure, weight, height, bodymass index, waist circumference) were collected for adults andchildren (ages 6-17) without known diabetes, and recorded in aclinical database. A general linear mixed effects model was appliedto get overall trend estimates for each risk factor longitudinally.Among adults (N=91), BMI, cholesterol (total), and blood pressuredid not change, and waist increased significantly. A1c tended toincrease (p-value = 0.05). At baseline 18% of adults tested wereidentified with pre-diabetes (fasting plasma glucose 6.1-6.9mmol/L), and 4% were identified with probable diabetes (FPG>/=7.0 mmol/L) (CDA-CPGs 2008). Among children (N=33): BMIand blood pressure percentiles, A1c and cholesterol (total) allincreased, though only BMI did so significantly.For those who have had at least one follow-up visit, results-over-time are not encouraging. Despite more than seven years ofsurveillance, and numerous prevention and activity initiatives andinfrastructure implemented within the community, the risk fordiabetes does not appear to be decreasing.1Believing we can Reduce Aboriginal Incidence of DiabetesDr. Ellen L. Toth,BRAID Medical LeadDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inDiabetes and Cardiovascular Risk inAdults without known diabetes, N = 91Adults without known diabetes, N = 91 Children without known diabetes, N = 33Children without known diabetes, N = 33BMI, cholesterol (total), andBMI, cholesterol (total), andblood pressure did not change,blood pressure did not change,and waist increasedand waist increasedsignificantly,significantly,Among adults, A1c tended toAmong adults, A1c tended toincrease (pincrease (p--value = 0.05). Atvalue = 0.05). Atbaseline 18% of adults testedbaseline 18% of adults testedwere identified with prewere identified with pre--diabetes (fasting plasmadiabetes (fasting plasmaglucose 6.1glucose 6.1--6.9 mmol/L), and6.9 mmol/L), and4% were identified with4% were identified withprobable diabetes (FPG >/=7.0probable diabetes (FPG >/=7.0mmol/L).mmol/L).Among children (N=33), allparameters increased, withBMI and waist achievingstatistical significanceSignificance =0.05Sig: 0.674Sig.: 0.016Sig.: 0.437Sig.:0.513Sig.:0.100Sig.:0.00Sig.:0.052Sig.:0.975Sig.:0.351Sig.:0.62Sig.:0.764Sig.:0.00Sig.:0.00

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