This book is, in some ways, written like a diet book, which isn't a terrible thing. But unlike other diet books I've read or even glanced through, which are largely fluffy polemics for the "hook" the author has in mind, this is written more like a scientific primer on the biochemistry of human metabolism and hormone function. It is fairly dense with good information, presented accessibly to a beginner.
The most disturbing revelation in this book is that the information supporting the authors' basic thesis--the relationship between macronutrients, the metabolic hormones insulin and glucagon, and disorders such as obesity, hypertension, high cholesterol and diabetes--is all basic human biochemistry and has been available to scientists, researchers and nutritionists throughout these last few decades and beyond in the form of basic medical textbooks. And yet, viewing nutrition through the prism of the demonization of saturated fat, particularly red meat, the nutritional establishment has not only failed to put the pieces together in the most obvious way, it has deliberately arranged them into bizarre pretzel-like configurations to support the prevailing (but illogical) view.
The authors' thesis fits the known biological facts of hormones and metabolism, it fits the known history of mankind, and it fits most common sense wisdom about nutrition and weight loss prior to the last few decades.
There are of course many nuances and individual variations that can make a difference in specific cases--but trying to build a nutrional model on any basis that contradicts this viewpoint is flat-out wrong. Bad science. And dangerous, particiularly if it suggests a high-carbohydrate diet to people who are obviously suffering from hyperinsulinemia (insulin resistance).
These facts are beyond question:
1) Insulin and glucagon, in addition to regulating blood sugar, also manage a host of other functions in the body, including fat storage and the manufacturing of cholesterol.
2) Ingested carbohydrates raise blood sugar, triggering the release of insluin, and thus temporarily raising the ratio of serum insulin to glucagon in order keep blood sugar from rising too high.
3) Excessive carbohydrate intake, over a long period of time, gradually decreases the cells' sensitivity to insulin, such that more and more insluin is necessary regulate blood sugar.
4) When serum insulin levels are consistently elevated, a host of metabolic disorders kick in, including excessive fat storage and excessive manufacture of cholesterol. (This, by the way, *not* dietary cholesterol, is the cause of high LDL in the blood.)
5) When this insulin resistence gets bad enough, the insulin is no longer able to keep blood sugar in a normal range, and adult-onset diabetes sets in.
If you're 19 years old and skinny, you don't need any intervention, but you would be well advised to learn to avoid taxing your system with the insane amount of sugar, flour and starches that most people who can "get away with it" eat, because it will make life much less difficult when you're 35, 45, 55.
If you're past your twenties, you're more than 15% overweight, and you have high blood pressure, high cholesterol or high triglycerides, you almost certainly have some degree of hyperinsulinemia (this can be confirmed with the right blood test), and grasping these concepts is going to be increasingly vital to your ability to regain or retain your health.
I will add that I began this diet at around age 35, and dropped from 220 to 185 (probably close to my ideal weight) in about two months, and did it without feeling at all deprived. I'm fortunate in that meat, eggs, cheese and green vegetables constitute a very enjoyable diet for me, so the induction phase was a breeze.
Read this book and learn about your hormones and your metabolism. There's a lot more than what I just summarized, all of it important. Then, from a position of knowledge, assess your own situation and see if the recommended diet will help you.
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