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Gen pathology finals pictures

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Transcript

  • 1. Finals Pictures
  • 2. Examples of MalformationsA. Polydactyly (one or more extra digits) and syndactyly (fusion of digits)B. Cleft lip (may be with or without associated cleft palate)C. Lethal malformation (midface structures are fused or ill-formed); external dysmorphogenesis associated with severe internal anomalies such as maldevelopment of the brain and cardiac defects
  • 3. Disruption by an amniotic bandDisruptions (Amniotic Bands)
  • 4. Oligohydramnios sequence Flattened facial features and deformed right foot (talipes equinovarus)
  • 5. Thalidomide Babies
  • 6. Fetal macrosomia in Gestational Diabetes
  • 7. Trisomy 21 (Down’s Syndrome)
  • 8. Trisomy 18 (Edward’s Syndrome) • unusually small head • back of the head is prominent • ears are malformed and low- set • mouth and jaw are small (may also have a cleft lip or cleft palate • hands are clenched into fists, and the index finger overlaps the other fingers • Clubfeet (or rocker bottom feet) and toes may be webbed or fused
  • 9. Trisomy 13 (Patau Syndrome)
  • 10. Hyaline Membrane Disease This is hyaline membrane disease due to prematurity and lack of surfactant production from type II pneumonocytes within the immature lung. Note the thick pink membranes lining the alveolar spaces.
  • 11. Necrotizing enterocolitis (NEC)
  • 12. Necrotizing enterocolitis (NEC) Pneumatosis instestinalis (air within the intestinal walls)The plain abdominal film shows air in the portal vein, air in the bowel walls, and a largepneumoperitoneum [subdiaphragmatic free air, perihepatic free air, double wall sign (bluearrows), triangle sign (green arrows), and falciform ligament (red arrow)].
  • 13. Hydrops Fetalis (non-immune) Cystic hygroma (in fetus w/ Turner’s syndrome) Generalized edema from fluid collection in the soft tissues results in hydrops fetalis. Causes: Most common are "non- immune" types that include infections, congestive failure (from anemia or cardiac abnormalities), and congenital anomalies. Immune hydrops, from maternal antibody formed against fetal red blood cells, is not common when Rh immune globulin is employed in cases of potential Rh incompatibility.
  • 14. Kernicterus
  • 15. Congenital Capillary Hemangioma At birth At 2 years After spontaneous regression
  • 16. Capillary Hemangioma RBC-filled capillaries
  • 17. LymphangiomaDilated lymphatic channels
  • 18. TeratomaMucus-secreting glands, cartilage, bone
  • 19. Neuroblastoma
  • 20. Acute Myeloid LeukemiaBM expansion
  • 21. Wilms Tumor, kidney nests and sheets of dark blue cells at the left with compressed normal renal parenchyma at the rightWilms tumor of the kidney (lobulated white-tan mass), many are associated with genetic defects onchromosome 11.Children present with abdominal enlargement from the mass effect.
  • 22. Carbon monoxide poisoning Cherry-red discoloration of the skin
  • 23. Asbestosis Asbestos fiber Tan-white pleural plaques Asbestos fibers coated with iron
  • 24. Lead Toxicity
  • 25. Arsenic poisoning
  • 26. Dental fluorosis
  • 27. Tetracycline-stained teeth
  • 28. Effects of Smoking
  • 29. ??????????
  • 30. Liver cirrhosis in chronic alcoholism (left)Esophageal varices associated with liver cirrhosis (right)
  • 31. Stevens-Johnson Syndrome SJS is defined as detachment of less than 10% of the body surface area
  • 32. Marasmus vs. Kwashiorkor
  • 33. Anorexia Nervosa
  • 34. Bulimia nervosa
  • 35. Bitot’s spot in Vit. A deficiency
  • 36. Rickets
  • 37. Scurvy
  • 38. Riboflavin deficiency
  • 39. Chickenpox vs. Shingles
  • 40. Mumps
  • 41. Measles
  • 42. Herpes Simplex
  • 43. CytomegalovirusOwl-eye inclusions in the lung tissue Blueberry-muffin baby
  • 44. Epstein-Barr virus
  • 45. DengueHermans rash – islands of white in a sea of red
  • 46. Human Papilloma Virus
  • 47. Cervical Cancer
  • 48. Poliomyelitis
  • 49. Strep throat
  • 50. Diphtheria
  • 51. Gram-negative intracellular diplococci
  • 52. Tetanus Opisthotonus(severe spastic paralysis)
  • 53. Syphilis (chancre)
  • 54. Entamoeba histolytica(cause of amoebiasis)
  • 55. Giardia lamblia(Giardiasis)
  • 56. Trichomonas vaginalis (Trichomoniasis) “Strawberry cervix" - cervical mucosa reveals punctate hemorrhages with accompanying vesicles or papules
  • 57. Ascaris lumbricoides(Giant intestinal roundworm) cause of Ascariasis
  • 58. Enterobius vermicularis Female worms leave the rectum during the night and deposit eggs on the perianal skin, producing pruritus.
  • 59. Tapeworm
  • 60. Schistosomiasis
  • 61. Candida albicans(Candidiasis-oral thrush) Yeast cells Pseudohyphae
  • 62. Ringworm Tinea cruris Tinea corporis
  • 63. Ameloblastoma
  • 64. Pleomorphic Adenoma
  • 65. Warthin’s Tumor
  • 66. Mucoepidermoid Carcinoma
  • 67. Adenoid Cystic Carcinoma
  • 68. Aneurysm Atherosclerotic aneurysm of the aorta (large "bulge“ just above the aortic bifurcation). Prone to rupture when they reach about 6 to 7 cm in size. Felt on PE as a pulsatile mass in the abdomen.
  • 69. Arteriovenous malformation (AVM)
  • 70. Atrial Septal Defect (ASD)
  • 71. Ventricular Septal Defect (VSD)
  • 72. Patent Ductus Arteriosus (PDA)
  • 73. Tetralogy of Fallot (TOF)
  • 74. Transposition of the Great Arteries
  • 75. GOODLUCK! 