Gen pathology finals pictures

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Gen pathology finals pictures

  1. 1. Finals Pictures
  2. 2. Examples of MalformationsA. Polydactyly (one or more extra digits) and syndactyly (fusion of digits)B. Cleft lip (may be with or without associated cleft palate)C. Lethal malformation (midface structures are fused or ill-formed); external dysmorphogenesis associated with severe internal anomalies such as maldevelopment of the brain and cardiac defects
  3. 3. Disruption by an amniotic bandDisruptions (Amniotic Bands)
  4. 4. Oligohydramnios sequence Flattened facial features and deformed right foot (talipes equinovarus)
  5. 5. Thalidomide Babies
  6. 6. Fetal macrosomia in Gestational Diabetes
  7. 7. Trisomy 21 (Down’s Syndrome)
  8. 8. Trisomy 18 (Edward’s Syndrome) • unusually small head • back of the head is prominent • ears are malformed and low- set • mouth and jaw are small (may also have a cleft lip or cleft palate • hands are clenched into fists, and the index finger overlaps the other fingers • Clubfeet (or rocker bottom feet) and toes may be webbed or fused
  9. 9. Trisomy 13 (Patau Syndrome)
  10. 10. Hyaline Membrane Disease This is hyaline membrane disease due to prematurity and lack of surfactant production from type II pneumonocytes within the immature lung. Note the thick pink membranes lining the alveolar spaces.
  11. 11. Necrotizing enterocolitis (NEC)
  12. 12. Necrotizing enterocolitis (NEC) Pneumatosis instestinalis (air within the intestinal walls)The plain abdominal film shows air in the portal vein, air in the bowel walls, and a largepneumoperitoneum [subdiaphragmatic free air, perihepatic free air, double wall sign (bluearrows), triangle sign (green arrows), and falciform ligament (red arrow)].
  13. 13. Hydrops Fetalis (non-immune) Cystic hygroma (in fetus w/ Turner’s syndrome) Generalized edema from fluid collection in the soft tissues results in hydrops fetalis. Causes: Most common are "non- immune" types that include infections, congestive failure (from anemia or cardiac abnormalities), and congenital anomalies. Immune hydrops, from maternal antibody formed against fetal red blood cells, is not common when Rh immune globulin is employed in cases of potential Rh incompatibility.
  14. 14. Kernicterus
  15. 15. Congenital Capillary Hemangioma At birth At 2 years After spontaneous regression
  16. 16. Capillary Hemangioma RBC-filled capillaries
  17. 17. LymphangiomaDilated lymphatic channels
  18. 18. TeratomaMucus-secreting glands, cartilage, bone
  19. 19. Neuroblastoma
  20. 20. Acute Myeloid LeukemiaBM expansion
  21. 21. Wilms Tumor, kidney nests and sheets of dark blue cells at the left with compressed normal renal parenchyma at the rightWilms tumor of the kidney (lobulated white-tan mass), many are associated with genetic defects onchromosome 11.Children present with abdominal enlargement from the mass effect.
  22. 22. Carbon monoxide poisoning Cherry-red discoloration of the skin
  23. 23. Asbestosis Asbestos fiber Tan-white pleural plaques Asbestos fibers coated with iron
  24. 24. Lead Toxicity
  25. 25. Arsenic poisoning
  26. 26. Dental fluorosis
  27. 27. Tetracycline-stained teeth
  28. 28. Effects of Smoking
  29. 29. ??????????
  30. 30. Liver cirrhosis in chronic alcoholism (left)Esophageal varices associated with liver cirrhosis (right)
  31. 31. Stevens-Johnson Syndrome SJS is defined as detachment of less than 10% of the body surface area
  32. 32. Marasmus vs. Kwashiorkor
  33. 33. Anorexia Nervosa
  34. 34. Bulimia nervosa
  35. 35. Bitot’s spot in Vit. A deficiency
  36. 36. Rickets
  37. 37. Scurvy
  38. 38. Riboflavin deficiency
  39. 39. Chickenpox vs. Shingles
  40. 40. Mumps
  41. 41. Measles
  42. 42. Herpes Simplex
  43. 43. CytomegalovirusOwl-eye inclusions in the lung tissue Blueberry-muffin baby
  44. 44. Epstein-Barr virus
  45. 45. DengueHermans rash – islands of white in a sea of red
  46. 46. Human Papilloma Virus
  47. 47. Cervical Cancer
  48. 48. Poliomyelitis
  49. 49. Strep throat
  50. 50. Diphtheria
  51. 51. Gram-negative intracellular diplococci
  52. 52. Tetanus Opisthotonus(severe spastic paralysis)
  53. 53. Syphilis (chancre)
  54. 54. Entamoeba histolytica(cause of amoebiasis)
  55. 55. Giardia lamblia(Giardiasis)
  56. 56. Trichomonas vaginalis (Trichomoniasis) “Strawberry cervix" - cervical mucosa reveals punctate hemorrhages with accompanying vesicles or papules
  57. 57. Ascaris lumbricoides(Giant intestinal roundworm) cause of Ascariasis
  58. 58. Enterobius vermicularis Female worms leave the rectum during the night and deposit eggs on the perianal skin, producing pruritus.
  59. 59. Tapeworm
  60. 60. Schistosomiasis
  61. 61. Candida albicans(Candidiasis-oral thrush) Yeast cells Pseudohyphae
  62. 62. Ringworm Tinea cruris Tinea corporis
  63. 63. Ameloblastoma
  64. 64. Pleomorphic Adenoma
  65. 65. Warthin’s Tumor
  66. 66. Mucoepidermoid Carcinoma
  67. 67. Adenoid Cystic Carcinoma
  68. 68. Aneurysm Atherosclerotic aneurysm of the aorta (large "bulge“ just above the aortic bifurcation). Prone to rupture when they reach about 6 to 7 cm in size. Felt on PE as a pulsatile mass in the abdomen.
  69. 69. Arteriovenous malformation (AVM)
  70. 70. Atrial Septal Defect (ASD)
  71. 71. Ventricular Septal Defect (VSD)
  72. 72. Patent Ductus Arteriosus (PDA)
  73. 73. Tetralogy of Fallot (TOF)
  74. 74. Transposition of the Great Arteries
  75. 75. GOODLUCK! 

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