3. Fructose intolerance is a
recessive genetic disease
in which the patients lack
the gene which code for
an enzyme called aldolase
B in the liver which is
responsible for digestion
of fructose and sucrose.
4. • Fructose is a 6C
compound
• It is a ketose
• It has a keto functional
group in the
Second carbon atom.
5.
6.
7. Nausea and vomiting if fructose or sucrose is consumed in any form.
Mild jaundice which can be observed as yellowish discoloration on the skin and sclera
Hypoglycemia if fructose is consumed
Dental caries is not seen in these patients.
8. Palpation Eye examination Liver biopsy
By palpation we
By examining the Biopsy can indicate the
can identify
eye we can identify Abnormal level of enzyme
hepatomegaly
the presence of Especially lack of aldolase B
and
jaundice which is
spleenomegaly
another symptom
which are the
of HFI.
symptoms of
HFI.
9.
10.
11.
12. Streptococcus mutans
Grown on selective agar
After gram staining medium like Lauria media
found to be gram (fructose and sucrose
positive rich).
13.
14. Fructose free diet is the best treatment for
avoiding complications like liver failure and death
It is unusually seen in children that they restrict
themselves from consuming sweets and chocolates
who suffer from this disorder.
15. * HFI
* Dental caries
* Microbiological basis of Dental
* Relation between HFI and Dental caries