Liposarcoma of spermatic cord e A rare entity
Pravin Govardhane a
, Feroz Amir Zafar a
, Ishfaq A. Geelani a
, H. Girish a
D.V.S.L.N. Sharma a
, V. Rajagopal a,
*, Meenakshi Swain b
, G. Swarnalatha b
Department of Urology, Apollo Hospitals, Hyderabad, India
Department of Histopathology, Apollo Hospitals, Hyderabad, India
a r t i c l e i n f o
Received 31 January 2013
Accepted 31 January 2013
Available online 6 February 2013
Spermatic cord tumors
a b s t r a c t
Introduction and objective: Liposarcoma of the spermatic cord is a rare entity with only two
series and less than 100 cases reported in literature. We report a case of a giant liposarcoma
of the spermatic cord.
Case report: A 65-year old man presented with a 2-year history of a progressive painless
swelling in the right lower quadrant of the abdomen. He gave a past history of right
inguinal hernia repair and excision of a mass lesion of the spermatic cord 15 years back
(? nature; no HPE report available). Local examination revealed a large smooth solid mass
about 20 Â 12 cm in the right iliac fossa and pelvis, ﬁrm, non-tender and mobile from side
to side. Testes were normal. USG revealed a non-homogenous and hyper echoic. CECT
showed a 21 Â 11.2 cm well deﬁned mass lesion with mixed densities (18 HU) and minimal
enhancement with contrast present in the right iliac fossa and pelvic region. On explora-
tion, a lipomatous mass was found arising from the inguinal portion of spermatic cord.
Radical orchiectomy with wide local excision was carried out. Histopathological exami-
nation of the resected specimen showed a well differentiated liposarcoma of the spermatic
cord (myxoid variant). Margins were negative. Patient was advised long-term follow up in
view of high recurrence rate.
Conclusion: Liposarcoma of the spermatic cord is rare. Surgical treatment is the manage-
ment of choice with Radical orchiectomy and wide local excision. Adjuvant radiation
should be given if margin status is in doubt. High incidence of local recurrence mandates
a long period of follow up.
Copyright ª 2013, Indraprastha Medical Corporation Ltd. All rights reserved.
Malignant lesions of the spermatic cord are rare with only
around 100 cases reported in the world literature.1
osarcoma of spermatic cord is a rare entity and only few cases
have been reported in literature.
Sarcomas of the spermatic cord, epididymis, and testis are
the most common genitourinary sarcomas in adults.
Liposarcoma is the most common histologic subtype in adults,
followed by rhabdomyosarcoma, leiomyoma, malignant
ﬁbrous histiocytoma, and ﬁbrosarcoma.2
Sarcomas are most often in the intrascrotal region and
primary mesenchymal tumors of the testis are uncommon.
These tumors usually present as a painless, palpable mass,
and most are large (>5 cm). Sarcomas should be managed
initially through an inguinal approach with wide excision of
* Corresponding author.
E-mail address: email@example.com (V. Rajagopal).
Available online at www.sciencedirect.com
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the spermatic cord and testis with high ligation.3
osarcomas rarely metastasize but tend to recur locally.4
We report a case of a giant liposarcoma of the spermatic
2. Case report
A 65-year old man presented with a 2-year history of a pro-
gressive painless swelling in the right lower quadrant of the
abdomen. He gave a past history of right inguinal hernia repair
and excision of a mass lesion of the spermatic cord 15 years
back (? nature; no HPE report available).
Local examination revealed a large smooth solid mass
about 20 Â 12 cm in the right iliac fossa and pelvis, ﬁrm, non-
tender and mobile from side to side (Fig. 3). Testes were
Routine blood investigations were within normal limits.
USG revealed a non-homogenous and hyper echoic mass in
right iliac fossa.
CECT showed a 21 Â 11.2 cm well deﬁned mass lesion with
mixed densities (18 HU) and minimal enhancement with
contrast present in the right iliac fossa and pelvic region (Figs.
1 and 2).
Inguinal exploration was done. We found a large lip-
omatous mass arising from the right inguinal cord (Fig. 4). We
performed a Radical orchiectomy with wide local excision.
Mass was sent for histopathological examination.
Histopathological examination of the resected specimen
showed a well differentiated liposarcoma of the spermatic
cord (myxoid variant) as shown in Figs. 5 and 6. Margins were
Lesauvage reported the ﬁrst case of sarcoma of spermatic cord
Most patients present in their 50s or 60s in the form of
a slow-growing inguinal or inguino-scrotal mass and they can
be mistaken for inguinal hernia or lipoma and CT or MRI is
Fig. 1 e CECT pelvis showing mass in iliac fossa with
Fig. 2 e CECT of pelvis showing mass in iliac fossa with
minimal enhancement on contrast.
Fig. 3 e Mass in right lower abdomen.
Fig. 4 e Large tumor dissected through inguinal
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helpful to distinguish between these entities. Embryonal
rhabdomyosarcoma is the most common histologic subtype
in men younger than age 30.3
A relatively higher incidence of this cancer has been
reported in Japanese men (nearly one-fourth of the reported
cases) but the cancer is known to occur all over the world.3
Liposarcoma accounts for 5e7% of paratesticular
Liposarcoma are further subdivided into 4 types, including
well differentiated, myxoid, round-cell, and pleomorphic.
Myxoid variety is the most common type and account for
about 50% of all liposarcomas.
Inguinal radical orchiectomy is the standard approach for
sarcomas of spermatic cord with wide resection margins.6
Some authors favor a hemiscrotectomy in addition to the
Local recurrence can occur in upto 50% patients.8
Since negative margin status can rarely be ensured, some
authors recommend adjuvant radiation9
although the efﬁcacy
of this approach is debated. The long-term survival of men
with paratesticular sarcoma is approximately 50%.
Liposarcoma of the spermatic cord is rare
Surgical treatment is the management of choice with Rad-
ical orchiectomy and wide local excision
Adjuvant radiation should be given if margin status is in
High incidence of local recurrence mandates a long period of
This is perhaps a recurrent liposarcoma of the spermatic
Conﬂicts of interest
All authors have none to declare.
r e f e r e n c e s
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of spermatic cord sarcoma. Cancer. 1996;77:1873.
Fig. 5 e Histopathological pictures of well deﬁned
liposarcoma of spermatic cord (myxoid variant).
Fig. 6 e Histopathological pictures of well deﬁned
liposarcoma of spermatic cord (myxoid variant).
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