Cleaning up chemistry for the pharma industry: delivering a flexible platform for interrogating the FDA DailyMed website
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The original abstract is below. Ultimately this work was not funded by Microsoft and we did not deliver it on Sharepoint Server. Nevertheless, we DO depend heavily on Microsoft Technology to do what ...
The original abstract is below. Ultimately this work was not funded by Microsoft and we did not deliver it on Sharepoint Server. Nevertheless, we DO depend heavily on Microsoft Technology to do what we do... .NET and SQL server specifically.
DailyMed is a website hosted by the FDA providing access to information about marketed drugs. This information includes FDA approved labels (package inserts) and provides a standard, comprehensive, up-to-date, look-up and download resource of medication content and labeling as found in medication package inserts. With an intention of enhancing the dataset by making it searchable by chemical structure/substructure we determined that the data contained numerous chemistry errors. We have therefore used a combination of text-mining, automated and manual curation to improve the quality of the data set. In so doing we have also made querying of the data more flexible. Specifically we have used the Microsoft Sharepoint technology to create a portal allowing both text-based and structure-based querying. We will report on the advantages such an approach delivers in terms of flexible interrogation of DailyMed.
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