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2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
2011 Environmental Sustainability Report Highlights
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2011 Environmental Sustainability Report Highlights

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As a global leader in human therapeutics, Amgen is committed to environmentally responsible operations. We welcome your comments on Amgen's 2011 Environmental Sustainability Reporting: …

As a global leader in human therapeutics, Amgen is committed to environmentally responsible operations. We welcome your comments on Amgen's 2011 Environmental Sustainability Reporting: esfeedback@amgen.com.

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  • 1. Amgen 2011 Environmental Sustainability Highlights
  • 2. Leadership MessageLeft: Kevin W. Sharer (left) Leadership Message business processes—from conserving almost 2,000and Robert A. Bradway. Amgen delivered results in 2011—among them, cubic meters of water a year in Rhode Island to reusing advancing our comprehensive environmental sustainability 72 percent of treated wastewater in Puerto Rico. We’reRight: Amgen’s facility plan. This environmental sustainability highlights proud of their efforts both within our Company and in in Seattle includes brochure describes how Amgen reduced our environmental our communities.low-water plantings. impact and integrated sustainable practices across the many complex activities we undertake to bring As we reflect on our achievements in 2011, Amgen is medicines to patients. already planning for the next phase of our environmental sustainability program that focuses on new targets for In 2011, Amgen exceeded four of our six 2012 2020 and continues to build sustainability into the way conservation targets —in energy, water, and recycling Amgen operates. and reduction of waste —and the Company is on course to meet carbon dioxide and fleet fuel efficiency targets this year. Amgen has cut millions of dollars in costs as a result of conservation efforts. Staff participation is the key to meeting our environmental Kevin W. Sharer Robert A. Bradway sustainability goals. Innovative Amgen staff members Chairman and Chief President and have found ways to conserve resources and improve our Executive Officer Chief Operating Officer 2
  • 3. This brochure, a supplement to Amgen’s 2011 Environmental Sustainability Report found at environment.amgen.com, highlights how we have successfully implemented an environmental sustainability plan in a data-driven and strategic way. Our approach is to focus on initiatives that both benefit the environment and help us become a more efficient and cost-effective company.Our Targets In 2008, we set six environmental targets: energy, carbon dioxide, water, waste recycling, waste reduction, and the fuel efficiency of our U.S. sales fleet. We identified these as areas where we initially could make the most progress in reducing both our environmental impacts and our business costs. We designed our targets so that we track our progress through deliberate efforts we make, without influence from growth or contraction in our business. We use a formal measurement process to confirm results. We’re proud that we have exceeded our energy, water, and waste targets, and we’re on track to achieve the remaining targets by the end of 2012. 2012 Target Percentage Complete Through Year-end 2011 Energy Reduce 500,000 gigajoules (GJ) 12% of 2007 baseline 723,000 GJ Carbon dioxide Reduce 75,000 metric tons (MT) 64,000 MT 18% of 2007 baseline Water Reduce 235,000 cubic meters (m3 ) 673,000 m3 7% of 2007 baseline Recycling Divert more than 40% 59 percent 2007 rate was 38% Waste Reduce 700 metric tons (MT) 875 MT 7% of 2007 baseline Fuel efficiency Improve by 4 miles per gallon (MPG) 3.9 MPG 23% of 2007 baseline 0% 50% 100% 150% 200% 250% 300% 3
  • 4. Amgen operates in 53 countries, with a physical presence in 45 countries. To limit our environmental impact, we share best practices across our global networks, and the projects we pilot at one location are often adapted for use at other facilities.Conservation Progress Across the NetworkLeft: Our Colorado facility Amgen Named Energy Partner facility’s effective program for continuous improvement,receives recognition from of the Year in Colorado the team had rerouted the pipe to send the water backthe state. In July 2011, Colorado governor John Hickenlooper to be used in the cooling tower water system, saving named Amgen the state’s Energy Partner of the Year. almost 2,000 cubic meters of water a year. The facilityCenter: Our Rhode Island The governor recognized Amgen Colorado for reducing estimates it’s saved more than 15,000 cubic meters offacility makes water energy usage overall by 15.5 percent at facilities in water total since 2009 from staff ingenuity and inputconservation a priority. Boulder and Longmont from 2008 through 2010, efforts such as this. that have helped make Colorado a leader in energyRight: A facility goes all efficiency. Amgen is one of 13 charter members of Making the Leap to Large-Scale Compostingout for composting. Colorado’s Industrial Energy Challenge, a voluntary In 2011, our facility in Colorado switched all disposable program for Colorado businesses that spend more food-service items—right down to straws and coffee than $200,000 a year in energy bills. stirrers—to compostable varieties. This was a choice that made good sense in this location. We’re striving Staff Resourcefulness Conserves a Vital Resource as a company to reduce waste sent to landfills, and Amgen is one of the largest users of water in Kent County, composting services are widely available for Colorado’s Rhode Island. As a good neighbor in this community, residents and businesses. The full-scale food-service the facility there has built a culture of diligence and composting at Amgen Colorado is not only more problem solving when it comes to water conservation. environmentally friendly; it also makes life a little Plant technicians closely observe conditions and easier for staff, who can now toss food-service waste equipment, ask questions, and pursue solutions to into one place instead of spending time sorting it into make a positive impact. various bins. As just one of many examples of that ethic, a senior As the program’s manager admits, the program is maintenance technician observed that a pipe associated not without challenges, but feedback has been with a cooling tower pump was running water to drain. overwhelmingly positive. Through food-service and “What if that water could be recycled?” he wondered. other composting programs, the facility diverted Just one week after reporting his discovery through the more than 30 metric tons of waste from landfills to a new life as garden soil in 2011. 4
  • 5. From developing molecules to constructing our facilities, we are seeking more-environmentally-responsible approaches in alignment with our business goals. Our Design for Environment program is integrating environmental sustainability into many core areas of Amgen’s business.Sustainable by DesignLeft: We renovated a Green Biology, Green Chemistry friendly and efficient but also that buildings can continuebuilding in Thousand Through Amgen’s Green Biology and Green Chemistry being efficient as they age.Oaks, California, that programs, our scientists are seeking ways to makecombines green building processes more efficient and to use greener compounds In 2011, we completed an extensive renovation of antechniques with enhanced and fewer resources in the development of our medicines. office building on our Thousand Oaks, California, campus,collaboration approaches. designed to achieve Leadership in Energy and Environmental Staff members are using a guide that assesses environmental Design (LEED) Gold status. The project concentrates allRight: Green chemistry properties of raw materials along with new technologies the knowledge we’ve compiled through our Sustainableand green biology to minimize the use of urea and phosphates. In 2011, we Design and Construction program in one project. Thepractices improve completed an assessment of changes we’re considering to building—a pilot project that may set a new standardefficiency. make manufacturing our biotechnology medicines more for the Company—combines green building techniques environmentally friendly and efficient. with modern workspace design and technology. Our Small Molecule Process and Product Development Green Packaging group has made significant improvements for selected We are moving forward with plans and programs to development molecules in reducing waste and enhancing reduce the environmental impact of our primary and process safety and robustness through green chemistry. secondary product packaging. Scientists are using e-notebooks, collaboration tools, and solvent-selection guides to make improvements that are In 2011, we developed a Green Packaging Assessment more environmentally responsible and efficient for early Process that evaluates the sustainability of new packaging research and clinical development. in the design phase. For existing packaging, we created a plan, for execution in 2012, to include recycling logos Green Building on paperboard product cartons that would encourage Through our Sustainable Design and Construction program, end users to send this secondary packaging to recycling we build features into facilities or retool systems on a after product use. In the area of primary packaging, we case-by-case basis to decrease energy and water use. launched a Sharps Mail-Back program for patients using We’ve adapted efficient practices to best fit our business, Enbrel® (etanercept). Through the program, injection often going above and beyond industry green standards. materials (sharps) are ultimately converted into a new This program provides guidelines to ensure not only that product, which is used in various industrial applications design, construction, and installation are environmentally and kept out of landfills. 5
  • 6. PerformanceConserving Resources EnergyEnergy conservation is an important activity for the health of the 2007–2010 Energy Use and Energy Use Avoided †environment and our Company. Energy conservation also has a Through Conservation Efforts (1,000 GJ)direct impact on the amount of carbon dioxide (CO2 ) we emit throughoperations. These are areas where we’ve made an active effort to 5,000gather the knowledge we’ve gained and share it across our facilities’ 245 407 542 723 4,000networks. In 2011, projects and initiatives we’ve executed both tolimit our environmental impact and to achieve our targets resulted 3,000in energy savings of approximately 181,000 gigajoules and a CO2 2,000 4,341 4,019 4,006 3,916 3,885 2011reduction of 15,000 metric tons (MT). 1,000Our improvement target for the fuel efficiency of our U.S. sales fleet 0has driven our approach to fleet management over the years. We’ve 2007 2008 2009 2010 2011steadily expanded fuel-efficient-vehicle choices available formobile staff, rotating less-fuel-efficient vehicles out of the fleet for Energy Use Energy Use Avoided † Through Conservation Effortsmore-efficient options that achieve 23 miles or more per gallon. † Value represents year-over-year, cumulative avoidance.Carbon Dioxide Fuel Efficiency2007–2011 CO 2 Emissions and CO 2 Emissions Avoided† 2007–2011 U.S. Fleet Fuel Use and Fuel Use AvoidedThrough Conservation Efforts (1,000 MT) Through Conservation (Per 1,000 Gal)*500 2,500 36 49400 19 64 2,000 347 380300 1,500 15 173200 413 389 410 406 378 1,000 1,498 1,443 1,297 1,849 1,794100 500 0 0 2007 2008 2009 2010 2011 2007 2008 2009 2010 2011 Total CO2 Emissions CO2 Emissions Avoided† Through Fuel Used Fuel Use Avoided Through Conservation Efforts Conservation Efforts† Value represents year-over-year, cumulative avoidance. *Chart represents annual avoidance. 6
  • 7. PerformanceWasteThe Waste Hierarchy as a Model for Our Waste-Reduction Goals Routine Waste Chart 2007–2011 by Waste Hierarchy (MT) 100% More Sustainable 249 358 442 875 90% 3,542 80% Reduction 4,037 5,190 70% 4,532 4,757 60% 807 Recycling, Composting, Reuse 50% 686 560 680 40% 687 Energy Recovery 30% 5,796 From Incineration 4,112 20% 3,618 3,690 3,713 Disposal 10% 0% 2007 2008 2009 2010 2011 Less Sustainable Reduction* Recycling, Energy Recovery Disposal Composting, Reuse From IncinerationWater2007–2011 Water Intake and Intake Avoided* Reducing Waste, Saving WaterThrough Conservation Efforts (1,000 m3) The commitment of our staff members to the recycling programs we’ve implemented has been impressive. By year-end 2011, we had exceeded3,500 our 2012 target for recycling by 50 percent. We’ve identified a multitude3,000 550 601 663 673 of ways to recycle, including composting landscape, food, and disposable2,500 food-service waste; sending lab plastics and other hard-to-recycle items2,000 like Styrofoam to be converted to new items; and reusing equipment and1,500 3,286 2,738 2,537 2,574 2,586 office supplies on-site. With this success as a foundation, we are actively1,000 shifting to the practice of reducing the waste we generate in the first place. 500 0 Amgen continuously strives to conserve water, a vital component of our 2007 2008 2009 2010 2011 medicines. Water conservation solutions we’ve implemented include a wastewater treatment plant in Puerto Rico that enabled approximately Water Intake Water Intake Avoided* Through Conservation Efforts 318,000 cubic meters of treated wastewater to be recycled on-site in 2011 and low-water landscaping and smart-irrigation controls at a*Value represents year-over-year, cumulative avoidance. variety of facilities. 7
  • 8. Amgen makes an impact in the communities in which we operate through direct volunteer work by staff members and through financial support from the Amgen Foundation. We are a good neighbor in the communities where we work and live.Volunteering and GivingLeft, far right: We removed Volunteering for the Environment The Foundation has funded a variety of environmentalmore than two metric Working in a life sciences organization, many Amgen organizations for several years, but in 2011 a focus wastons of trash during the staff members share a deep appreciation for the natural placed on water quality, a key resource for Amgen’s2011 International world and enthusiastically volunteer for a range of business. The Foundation gave grants to the followingCoastal Cleanup. activities to help protect and sustain the environment. nonprofit organizations in the region surrounding the In 2011, staff members from California, Canada, Thousand Oaks, California, headquarters: Heal the Bay,Center: The Amgen Puerto Rico, Rhode Island, and Washington participated for education and outreach projects; the SurfriderFoundation supports in International Coastal Cleanup (ICC) events as part Foundation, for grassroots environmental educationenvironmental education of a worldwide effort to clear debris from coastal and efforts; Santa Barbara Channel Keeper, for theand habitat conservation. inland waterways. Staff members removed more than Ventura River Watershed Protection program; and two metric tons (4,400 pounds) of debris in 2011— The Nature Conservancy, for protection and restoration quadruple the amount from Amgen’s efforts in the 2010 of Santa Cruz Island. ICC. Individual facilities participated in many other cleanup and restoration events throughout the year such as Save Additionally, the Amgen Foundation funded other the Bay in Rhode Island, Anacapa Island plant restoration environmentally oriented nonprofits such as NatureBridge, events in the California Channel Islands, and a cleanup of for environmental education programming; the National the Charles River watershed in Massachusetts. Amgen Wildlife Federation’s Eco-Schools USA program for has recognized the passion and commitment of staff expanding the program’s presence in K–12 schools in environmental volunteers through Volunteer of the Year Ventura County, California; and the Washington Trails and Environmental Champions awards programs. Association’s Youth Trail Stewardship program, for trail maintenance by youth volunteers. The Amgen Foundation Supports the Environment The Amgen Foundation seeks to advance science See the Amgen Foundation 2011 Charitable Contributions education, improve quality of care and access for Report for more information on the wide variety of patients, and support resources that create sound nonprofits the Foundation supports in communities communities where Amgen staff members live and work. across the United States, Puerto Rico, and Europe. 8
  • 9. 2011 Environmental Sustainability Report GRI IndexAmgen reports in alignment with the Global Reporting Initiative (GRI) G3.1 guidelines. The GRI guidelines offer a useful framework to help companies standardize theirsustainability reporting. We are reporting on our 2011 performance at an application level C+, which has been GRI checked. See environment.amgen.com (GRI Check).The scope of the environmental data in our report includes 13 manufacturing, research and development, and distribution facilities in North America and Europe. These facilitiesrepresent approximately 93 percent of our operations, based on the square footage of our facilities. The remaining square footage primarily includes administrative offices.Our 2011 environmental data for this report has undergone limited assurance by Bureau Veritas.In 2011, Amgen divested of its Fremont, California, facility and acquired facilities in Dun Laoghaire, Ireland; Woburn, Massachusetts; and São Paulo,Brazil. In our 2011 report, data is included from our Dun Laoghaire facility—which we purchased in May—beginning in May through the end of the year.No data will be included for our Woburn or São Paulo facilities in this report, as we are still working through the integration process for these facilities.The index summarizes Amgen’s disclosures in relation to the GRI G3.1 indicators.Strategy and AnalysisNumber Disclosure Reported Response1.1 Statement from CEO environment.amgen.com (Leadership Message)Organizational ProfileNumber Disclosure Reported Response2.1 Name of organization Amgen2.2 Primary brands, products, and/or services www.amgen.com (Product websites)2.3 Operational structure www.amgen.com (Amgen Fact Sheet)2.4 Location of headquarters Thousand Oaks, CA2.5 Countries of operation www.amgen.com (Amgen Fact Sheet)2.6 Nature of ownership www.amgen.com (Amgen Fact Sheet)2.7 Markets served www.amgen.com (Amgen Fact Sheet)2.8 Scale of the reporting organization www.amgen.com (Amgen Fact Sheet) Amgen divested of its Fremont, California, facility in early 2011. Amgen acquired three facilities in 2011 in the following locations: Dun Laoghaire, Ireland; Woburn, Massachusetts; and São Paulo, Brazil. In 2011, Kevin Sharer announced plans to step down from his role as2.9 Significant changes during the reporting period Amgen’s CEO on May 23, 2012, and to retire from the Board and the Company at the end of 2012. Robert Bradway is expected to become the Company’s new CEO effective May 23, 2012, and the Board of Directors has announced their intention to elect Mr. Bradway as Chairman of the Board when Mr. Sharer retires from that position at the end of 2012.2.10 Awards environment.amgen.com (Environmental Awards and Recognition)Report ParametersNumber Disclosure Reported Response3.1 Reporting period January 1, 2011, to December 31, 20113.2 Date of most recent report May 20113.3 Reporting cycle Annual3.4 Contact point esfeedback@amgen.com environment.amgen.com (Amgen’s Environmental Sustainability Plan)3.5 Process for defining report content environment.amgen.com (Stakeholder Engagement) Amgen facilities within the scope of this report are as follows: United States: Thousand Oaks, California; Cambridge, Massachusetts; Greenwich, Rhode Island; Louisville, Kentucky; South San Francisco, California; Boulder and Longmont, Colorado; Juncos, Puerto Rico; Seattle and Bothell, Washington; Field Sales-U.S. Fleet3.6 Boundary of the report Canada: Burnaby, British Columbia Europe: Breda, Netherlands; Uxbridge and Cambridge, United Kingdom; Dun Laoghaire, Ireland Note: Amgen acquired the Dun Laoghaire facility in May, so data from this facility will be included only from May 2011 through December 2011.Reported Partial
  • 10. 2011 Environmental Sustainability Report GRI IndexReport Parameters (continued)Number Disclosure Reported Response Items that are out of scope for this report include global sales and administrative offices with minimal environmental impact; outsourced activities, such as contract manufacturers and suppliers; and3.7 Limitations on the scope and boundary of the report newly acquired Amgen facilities in São Paulo, Brazil, and Woburn, Massachusetts. Data from Amgen’s newly acquired facility in Dun Laoghaire, Ireland, will be included from May 2011 through December 2011 in this report. The in-scope facilities listed in indicator 3.6 represent our 13 manufacturing, research and development, and distribution facilities in North America, Europe, and Puerto Rico. These facilities represent3.8 Limitations on the scope and boundary of the report 93 percent of our operations, based on the square footage of our facilities. The remaining square footage primarily includes administrative offices. We do not include environmental data from outsourced activities or suppliers in this report.3.9 Basis for reporting environment.amgen.com (Summary of Data Notes)3.10 Explanation of the effect of any restatements No restatements Amgen divested of its Fremont, California, facility in early 2011. Amgen acquired three facilities in 2011 located in Dun Laoghaire, Ireland; Woburn, Massachusetts; and São Paulo, Brazil. For the 2011 report,3.11 Significant changes from previous reporting periods environmental data from the Dun Laoghaire facility is included from May 2011 through December 2011. The Woburn, São Paulo, and Fremont facilities will not be included.3.12 GRI content index table environment.amgen.com (GRI Index)Governance, Commitments, and EngagementNumber Disclosure Reported Response environment.amgen.com (Governance)4.1 Governance structure including committees www.amgen.com (Corporate Governance) In 2011 Kevin Sharer was both CEO and Chairman of the Board. Indicate whether the chair of the highest governance body is also an executive4.2 For more information on Amgen’s Board, see amgen.com officer (Corporate Governance)4.3 Unitary board structure www.amgen.com (Corporate Governance) Mechanisms for shareholders and employees to provide recommendations/direction4.4 www.amgen.com (Corporate Governance) to highest governance board4.14 List of stakeholder groups engaged by the organization environment.amgen.com (Stakeholder Engagement)4.15 Basis for identification and selection of stakeholders with whom to engage environment.amgen.com (Stakeholder Engagement)Economic Performance IndicatorsNumber Disclosure Reported Response environment.amgen.com (Summary of Data and Data Notes)EC1 Economic Performance: Direct economic value generated and distributed www.amgen.com (2011 Annual Report and Financial Summary) We’re actively working to conserve energy and reduce greenhouse gas emissions that result from our operations. We have also identified Economic Performance: Financial implications and other risks and opportunities due potential risks to our business associated with climate change suchEC2 to climate change as extreme weather events, water scarcity, and increasing regulation. Having plans in place to mitigate these risks increases the overall sustainability of the business. Indirect Economic Impacts: Understanding and describing significant indirectEC9 www.amgen.com (AmgenAssist) economic impacts, including the extent of impactsReported Partial
  • 11. 2011 Environmental Sustainability Report GRI IndexEnvironmental Performance IndicatorsNumber Disclosure Reported Response environment.amgen.com (Energy Sources)EN3 Energy: Direct energy consumption by primary energy source environment.amgen.com (Summary of Data) environment.amgen.com (Energy Sources)EN4 Energy: Indirect energy consumption by primary source environment.amgen.com (Summary of Data) environment.amgen.com (Energy Approach)EN5 Energy: Energy saved due to conservation and efficiency improvements environment.amgen.com (Summary of Data) environment.amgen.com (Targets) environment.amgen.com (Energy Approach)EN7 Energy: Initiatives to reduce indirect energy consumption and reductions achieved environment.amgen.com (Targets) environment.amgen.com (Water Approach)EN8 Water: Total water withdrawal by source environment.amgen.com (Summary of Data) environment.amgen.com (Water Approach)EN10 Water: Percentage and total volume of water recycled and reused environment.amgen.com (Summary of Data) Emissions, Effluents and Waste: Total direct and indirect greenhouse gas emissions environment.amgen.com (CO2 Performance)EN16 by weight environment.amgen.com (Summary of Data) environment.amgen.com (Energy and CO2 Performance) Emissions, Effluents and Waste: Initiatives to reduce greenhouse gas emissions andEN18 environment.amgen.com (Summary of Data) reductions achieved environment.amgen.com (Targets)EN22 Emissions, Effluents and Waste: Total weight of waste by type and disposal method environment.amgen.com (Summary of Data)EN23 Emissions, Effluents and Waste: Total number and volume of significant spills There were no significant spills in 2011. Products and Services: Percentage of products sold and their packaging materialsEN27 environment.amgen.com (Stakeholder Engagement) that are reclaimed by category In 2011 Amgen received two environmental notices of violation as a Compliance: Monetary value of significant fines and total number of non-monetaryEN28 result of agency inspections. There were no fines associated with these sanctions for non-compliance with environmental laws and regulations notices of violation.Labor Practices and Decent Work Performance IndicatorsNumber Disclosure Reported ResponseLA7 Occupational Health and Safety: Health and safety rates environment.amgen.com (Safe Workplace) Occupational Health and Safety: Programs in place to assist workforce, families andLA8 environment.amgen.com (Staff Wellness) communities regarding serious diseasesSociety Performance IndicatorsNumber Disclosure Reported Response Total value of financial and in-kind contributions to political parties, politicians, www.amgen.com (Corporate Governance)SO6 and related institutions environment.amgen.com (Summary of Data)Product Responsibility Performance IndicatorsNumber Disclosure Reported Response Customer Health and Safety: Life cycle stages in which health and safety impactsPR1 of products are assessed for improvement, and percentage of products subject to www.amgen.com (Medicine Safety) such proceduresReported Partial
  • 12. 2011 Environmental Sustainability Report Summary of DataEnergy (a)Type Unit 2007 2008 2009 2010 2011Combustion On-site (Direct) (d) 1,000 GJ 2,151 1,914 1,941 1,905 1,887Purchased Energy (Indirect) (e) 1,000 GJ 2,190 2,104 2,065 2,011 1,998Total Energy 1,000 GJ 4,341 4,019 4,006 3,916 3,885Total Energy Normalized to Net Sales 1,000 GJ/$B net sales 303 274 279 267 254Confirmed Results of Energy Reduction Projects (b, c) 1,000 GJ - 245 407 542 723Carbon Dioxide (CO2 ) (a )Type Unit 2007 2008 2009 2010 2011CO 2 Combustion On-site (Scope 1) (f) 1,000 MT 126 112 115 113 104CO 2 Purchased Energy (Scope 2) (g) 1,000 MT 287 276 295 292 275Total CO 2 From Energy 1,000 MT 413 389 410 406 378Total CO 2 Normalized to Net Sales 1,000 MT/$B net sales 28.9 26.5 28.6 27.7 24.7Total CO 2 Normalized to Total Energy MT/GJ 0.095 0.097 0.102 0.104 0.097Confirmed Results of CO 2 Reduction Projects (b, c) 1,000 MT - 19 36 49 64Other Carbon Dioxide (CO2 ) (h )Type Unit 2007 2008 2009 2010 2011CO 2 U.S. Sales Fleet (Scope 1) 1,000 MT 13 13 11 16 16CO 2 U.S. Sales Fleet Emissions Avoided (Scope 1) 1,000 MT - 0.1 2 3 3CO 2 Executive Air Fleet (Scope 1) 1,000 MT 5 5 5 7 7CO 2 Business Travel - Commercial (Scope 3) (i, j) 1,000 MT - - 31 36 50Water (a)Type Unit 2007 2008 2009 2010 2011Total Water Withdrawal (k, c) 1,000 CM 3,286 2,738 2,537 2,574 2,586 Municipal 1,000 CM 3,249 2,724 2,526 2,561 2,569 Other - (Reservoir) Trucked In 1,000 CM 8 8 6 - - Ground 1,000 CM 29 7 5 14 17Total Water Withdrawal Normalized to Net Sales 1,000 CM/$B net sales 230 186 177 176 169Water Fate 1,000 CM - - 2,532 2,576 2,584 Recycled 1,000 CM - - 376 453 533 Consumed Into Products 1,000 CM - - 20 20 20 Lost to Evaporation 1,000 CM - - 649 736 633 Discharged to Treatment 1,000 CM - - 1,553 1,554 1,663 Discharged Directly to Environment 1,000 CM - - 310 267 267Percentage of Water Recycled per Total Water Withdrawal % - - 15 18 21Confirmed Results of Water Reduction Projects (b) 1,000 CM - 550 601 663 673Waste (a, c)Type Unit 2007 2008 2009 2010 2011Recycling Rate (l) % 38 49 57 58 59Total Routine Waste MT 10,146 8,835 8,710 9,127 9,591 Hazardous Waste MT 1,343 1,065 1,003 1,154 1,115 Recycled MT 251 266 225 209 235 Incinerated for Energy Recovery MT 375 235 219 254 291 Incinerated Not for Energy Recovery MT 523 472 446 524 424 Landfilled MT 118 81 108 161 146 Treated (m) MT 76 11 6 6 20
  • 13. 2011 Environmental Sustainability Report Summary of DataWaste (a, c) (conti nued)Type Unit 2007 2008 2009 2010 2011 Nonhazardous Waste MT 8,803 7,770 7,706 7,972 8,475 Composted MT 260 317 408 524 477 Reused MT 32 87 87 57 60 Recycled MT 2,999 3,368 3,812 3,967 4,419 Incinerated for Energy Recovery MT 432 451 341 426 396 Incinerated Not for Energy Recovery MT 194 190 128 131 176 Landfilled MT 4,885 3,358 2,930 2,867 2,939 Treated (m) MT 0 0 0 0 8Total Routine Waste Normalized to Net Sales MT/$B net sales 709 602 607 623 627Total Nonroutine Waste (n) MT 31,400 54,800 80,000 23,599 12,459Confirmed Results of Routine Waste Reduction Projects (b) MT - 249 358 442 875FleetType Unit 2007 2008 2009 2010 2011U.S. Sales Fleet Fuel Efficiency (o) MPG-US 19 19 21 22 22.6U.S. Sales Fleet Fuel Use Avoided 1,000 GL - 15 173 347 380U.S. Sales Fleet Fuel Use 1,000 GL 1,498 1,443 1,297 1,849 1,794Business ProfileType Unit 2007 2008 2009 2010 2011Net Sales $B 14.311 14.687 14.351 14.660 15.295"Adjusted" Net Income (q) $B 4.804 4.885 5.014 5.024 4.858"Adjusted" R&D Investment (q) $B 3.064 2.910 2.739 2.773 3.116Corporate Political Contributions (U.S.) (p) $Mil 0.584 0.777 0.424 1.144 0.704Staff # FTE 17,500 16,900 17,200 17,400 17,800Health and SafetyType Unit 2007 2008 2009 2010 2011Absenteeism (r) Percent days away 2.4 2.1 2.1 2.0 2.1 Number of injuries and illnessesInjury and Illness Rate (Beyond First Aid) (s,c) 0.81 0.76 0.55 0.57 0.65 per 100 staff members Injuries with days away from workLost-Day Case Rate (t) 0.25 0.28 0.19 0.17 0.17 per 100 staff members Number of days away from workSeverity Rate (u,c) 8.20 10.05 7.82 5.9 4.93 per 100 staff membersFatalities # Fatalities 0 0 0 0 0Contractor Injury and Illness Rate (Beyond First Aid) (v) Incidents per 100 contractors 0.53 0.65 1.29 1.27 1.28Contractor Lost-Day Case Rate (v) Incidents per 100 contractors 0.07 0.07 0.27 0.61 0.61Contractor Fatalities # Fatalities 0 0 0 0 0Compliance (a)Type Unit 2007 2008 2009 2010 2011Environmental Notices of Violation (NOVs) (w) # NOVs 8 0 2 3 2
  • 14. 2011 Environmental Sustainability Report Summary of Data — NotesGeneral Amgen has included data from 13 facilities for energy and carbon dioxide, water, and waste. Those facilities represent approximately 93 percent of Amgen’s worldwide facility space based on total square feet. Included facilities are in Thousand Oaks, California, U.S.; Greenwich, Rhode Island, U.S.; Boulder and Longmont, Colorado, U.S.; Seattle and Bothell, Washington, U.S.; Juncos, Puerto Rico, U.S.; Louisville, Kentucky, U.S.; South San Francisco, California, U.S.; Cambridge, Massachusetts, U.S.; Burnaby, Canada; Breda, (a) Netherlands; Dun Laoghaire, Ireland; and Uxbridge and Cambridge, United Kingdom. This includes leased buildings where we have operational control over building infrastructure, including utilities. In 2011, Amgen divested of its Fremont, California, facility and acquired facilities in Dun Laoghaire, Ireland; Woburn, Massachusetts; and São Paulo, Brazil. In our 2011 report, data will be included from our Dun Laoghaire facility—which we purchased in May—beginning in May through the end of the year. No data will be included for our Woburn or São Paulo facilities in this report, as we are still working through the integration process for these facilities. Measurement and verification of conservation and reduction projects for energy and carbon dioxide, water, and waste are based on adaptation of the International Performance (b) Measurement and Verification Protocol (IPMVP), Concepts and Options for Determining Energy and Water Savings Volume 1, EVO 1,0000-1.2007, April 2007. Project measurements are conducted using reasonable means, including direct measurements and scientific estimations as appropriate. (c) Small changes to 2007–2010 data and progress toward targets previously reported have occurred due to refinements in calculations.Energy Direct energy use results from the operation of equipment that is owned or controlled by Amgen at the facilities listed in note (a). Data on the use of natural gas, propane, and diesel in boilers, furnaces, and HVAC are recorded from utility bills or purchase records. Data on the use of diesel in emergency generators are recorded from purchase records or meter (d) readings and, in some cases, estimated from run-hours. Utility bills recorded in units of volume are converted to energy by using the Global Reporting Initiative Version 3.0, EN3 table, to convert volumes of primary sources (natural gas, diesel), or from specific fuel analysis data (diesel used in Juncos, Puerto Rico), and the U.S. Energy Information Administration/ Annual Energy Review Table A1 (propane). Energy from emergency generators recorded as run-hours is estimated using the manufacturer’s specified fuel-feed rate for each generator. Indirect energy use results from purchased energy in the forms of electricity and steam at the Amgen facilities listed in note (a). Data on the use of electricity and steam are recorded (e) from utility bills. Utility bills for purchased steam that are recorded in units of mass (i.e., ‘lb steam’) are converted to energy by using the latent heat of evaporation from the saturated steam tables, then dividing by the efficiency of the supplier’s steam generator.Carbon Dioxide (CO2 ) Scope 1 CO2 emissions result from direct energy sources defined in note (c). CO2 emissions from our U.S. sales fleet and executive air fleet are found in the Other Carbon Dioxide category in this data summary. CO2 data from natural gas sources are calculated using regional specific emission factors from U.S. EPA Rule Part 98A Table C-3 (U.S. weighted average) for all U.S. sites; from the Ireland UFCCC for Amgen’s facility in Dun Laoghaire, Ireland; from U.K. Defra/DECC’s 110819 Guidelines for Amgen’s facilities in the United Kingdom (Uxbridge and Cambridge); from the NL Agency standard CO2 emission factors for Amgen’s facility in the Netherlands (Breda); and from the Methodology for Reporting 2011 Version 2.0/Ministry of Environment Victoria, B.C., December 2011, for Amgen’s facility in Burnaby, Canada. CO2 emissions data from propane and diesel fuel sources (except (f) Amgen’s facility in Juncos, Puerto Rico) are calculated using the Greenhouse Gas Protocol Cross-Sector Tools-Stationary Combustion-V.1.0 (Sept 2011). CO2 from diesel use in Amgen’s Juncos, Puerto Rico, facility are calculated using specific fuel analysis information and from U.S. EPA Rule Part 98A Table C-1. CO2 data from direct energy sources prior to 2011 were calculated using emission factors from the Greenhouse Gas Protocol Cross-Sector Tools-Stationary Combustion-V.1.0 (Jul 2009). Scope 1 emissions that are not included in this data summary include fugitive emissions from chillers, coolers, and HVAC, as well as process-related emissions from cell respiration (CO2 as a by-product) and pH adjustments (CO2 injection). Analysis of these sources in 2009 showed that our fugitive emissions are less than 1 percent of total carbon emissions when compared with other sources such as energy use and that cell respiration and emissions from pH adjustments are negligible (less than 0.1 percent of our total CO2 emissions). Scope 2 CO2 emissions result from indirect energy sources defined in note (d). CO2 data from purchased electricity are calculated using emission factors from U.S. EPA eGRID2010 10/11/2011 Version 3.2 (2007 data: eGRID subregion annual CO2 output emission rate) for all U.S. locations (HICC subregional factor is applied to Amgen Puerto Rico); from the Greenhouse Gas Division, Environment Canada (2006 data)-V.1.0 (April 2009) for Amgen’s facility in Burnaby, Canada; and from specific utility annual providers’ reports for Amgen (g) facilities in the United Kingdom (Uxbridge and Cambridge), the Netherlands (Breda), and Dun Laoghaire, Ireland. CO2 data from purchased steam are calculated using the Emission Factor for Natural Gas as identified in U.S. EPA Rule Part 98A Table C-3 (U.S. weighted average) for Amgen’s facility in Cambridge, Massachusetts. CO2 data from indirect energy sources prior to 2011 were calculated using emission factors from U.S. EPA eGRID2007 Version 1.1 for U.S. facilities.Other Carbon Dioxide (CO2 ) The Other Carbon Dioxide category contains Scope 1 and Scope 3 CO2 emissions that are tracked but not included in our current CO2 reduction target. CO2 emissions from our (h) executive air fleet are calculated using emission factors from the Greenhouse Gas Protocol Cross-Sector Tools-Transport-Fuel-Use (Sept 2011). CO2 emissions from our U.S. sales fleet are calculated using emission factors from the GHG Protocol Emission Factors for Petrol passenger cars (volume) (GHG Protocol) = 8.81 kg/gal. Fuel use and mileage data are collected at the pump for each vehicle. CO2 emissions from our commercial business travel are calculated by Amgen’s travel provider using the Defra tool. Scope 3 CO2 emissions are a consequence of the activities of the Company but occur from sources not owned or controlled by the Company. Scope 3 CO2 emissions that are (i) currently tracked include emissions from Amgen’s commercial business travel (air and rail.) (j) Commercial business travel was not tracked in 2007 or 2008.Water (k) Water intake in 2010 includes 2,564 thousand cubic meters from municipal sources and 14 thousand cubic meters from groundwater.Waste (l) Recycling rate is the proportion of waste that is recycled and reused compared with the total volume of routine, nonhazardous waste generated with potential for landfill disposal. Treatment means the physical, thermal, chemical, or biological processes that change the characteristics of the waste in order to reduce its volume or hazardous nature, facilitate its (m) handling, or enhance recovery. (n) Nonroutine waste constitutes waste generated outside the normal operations of our facilities and consists mainly of construction and demolition waste.Fleet (o) Measurement equivalents: 23.0 MPG-U.S. = 27.6 MPG-Imperial = 10.2 L/100KM = 9.78 KM/L
  • 15. 2011 Environmental Sustainability Report Summary of Data — NotesBusiness Profile Corporate political contributions represent Amgen Inc.’s aggregate contributions among those states where these are permissible. Corporate political contributions to certain (p) candidates for state and local elected offices are permissible in accordance with applicable laws and Amgen policy. Additional information may be found in the Corporate Governance section at www.amgen.com. (q) Amgen Inc. Reconciliation of GAAP Net Income to “Adjusted” Net Income (Unaudited) ($ in billions) Results for the years ended December 31, 2011 2010 2009 2008 2007 GAAP net income $3.683 $4.627 $4.605 $4.052 $3.078 Adjustments to GAAP net income: Legal settlements (a) 0.786 (0.001) 0.033 0.288 0.034 Amortization of acquired intangible assets, 0.294 0.294 0.294 0.294 0.295 product technology rights (b) Incremental non-cash interest expense (c) 0.143 0.266 0.250 0.235 0.219 Restructuring and cost savings initiatives (d) 0.097 - 0.070 0.148 0.739 Stock option expense (e) 0.085 0.124 0.115 0.103 0.181 Charges associated with the Fremont manufacturing 0.065 0.118 - - - facility transaction (f) Other merger-related expenses (g) 0.027 - - 0.001 0.036 Amortization of acquired intangible assets, research and 0.021 0.070 0.070 0.070 0.071 development (R&D) technology rights (h) Write-off of inventory (i) - - - 0.084 0.090 Write-off of acquired in-process R&D (j) - - - - 0.590 Other - - - - 0.054 1.518 0.871 0.832 1.223 2.309 Tax effect of the above adjustments (k) (0.331) (0.318) (0.293) (0.390) (0.491) Tax benefit resulting from prior-period charges (l) (0.012) (0.005) (0.018) - - Tax settlement (m) - (0.151) (0.087) - (0.092) California tax law change (n) - - (0.025) - - “Adjusted” net income $4.858 $5.024 $5.014 $4.885 $4.804 Reconciliation of GAAP R&D Expense to “Adjusted” R&D (Unaudited) ($ in billions) Results for the years ended December 31, 2011 2010 2009 2008 2007 GAAP R&D expense $3.167 $2.894 $2.864 $3.030 $3.266 Adjustments to GAAP R&D expense: Stock option expense (e) (0.035) (0.051) (0.049) (0.046) (0.083) Amortization of acquired intangible assets, (0.021) (0.070) (0.070) (0.070) (0.071) R&D technology rights (h) Other merger-related expenses (g) (0.007) - - (0.001) (0.029) Restructuring and cost savings initiatives (d) 0.012 - (0.006) (0.003) (0.019) “Adjusted” R&D expense $3.116 $2.773 $2.739 $2.910 $3.064
  • 16. 2011 Environmental Sustainability Report Summary of Data — NotesBusiness Profile (continued) (q) Notes for Reconciliation of GAAP (a) To exclude loss accruals or awards for legal settlements. (b) To exclude the non-cash amortization of product technology rights acquired in a prior-year business combination. (c) To exclude the non-cash interest expense associated with our convertible notes. (d) To exclude restructuring and cost savings initiatives charges and related expense reversals. (e) To exclude stock option expense. (f) To exclude charges as a result of our transaction with Boehringer Ingelheim involving our Fremont, California, manufacturing facility. (g) To exclude merger-related expenses. (h) To exclude the non-cash amortization of the R&D technology intangible assets acquired in business combinations in prior years. To exclude the write-off of inventory resulting from, in 2008, a strategic decision to change manufacturing processes and, in 2007, changing regulatory and (i) reimbursement environments. (j) To exclude the non-cash expense associated with writing off the acquired in-process R&D related to business combinations in prior years. The tax effect of the adjustments between our GAAP and “Adjusted” results takes into account the tax treatment and related tax rate(s) that apply to each adjustment in the applicable tax jurisdiction(s). Generally, this results in a tax impact at the U.S. marginal tax rate for certain adjustments, including amortization of intangible (k) assets and non-cash interest expense associated with our convertible notes, whereas the tax impact of other adjustments, including the charge for certain legal proceedings and stock option expense, depends on whether the amounts are deductible in the tax jurisdictions where the expenses are incurred or the asset is located and the applicable tax rate(s) in those jurisdictions. (l) To exclude the tax benefit related to certain prior-period charges excluded from “Adjusted” earnings. (m) To exclude the net tax benefit recognized as the result of resolving certain non-routine transfer-pricing issues with tax authorities. To exclude the net tax benefit resulting from adjustments to previously established deferred taxes, related primarily to prior acquisitions and stock option expense, due (n) to changes in California tax law effective in 2011.Health and Safety Absentee rate is based on U.S. staff members, including full-time, part-time, management, and nonmanagement. Hours recorded for family medical leave are divided by hours staff (r) members were expected to work to calculate the absenteeism rate (percent). Injury and illness rate is calculated based on the number of reported Amgen staff member injuries and illnesses beyond first aid. The rate is based on the number of injuries and (s) illnesses per 100 Amgen staff members. Data as of March 14, 2011. (t) Lost day case rate is the number of injury and illness cases involving days away from work per 100 Amgen staff members. Data as of March 14, 2011. (u) Severity rate is the actual number of days away from work due to injury or illness per 100 Amgen staff members. Data as of March 14, 2011. In 2009, we expanded our data tracking to include all contractors that work at our facilities. Previously the 2007 and 2008 data only included contractors working on large capital (v) construction projects.Compliance (w) Notices of violation (NOVs) reported that resulted from agency inspections.
  • 17. 2011 Environmental Sustainability Report Summary of Data — Assurance INDEPENDENT VERIFICATION STATEMENT Introduction and objectives of work Bureau Veritas North America, Inc. (Bureau Veritas) has been engaged by Amgen to conduct an independent assurance of selected environmental data included in Amgen’s 2011 Environmental Sustainability Report. This Assurance Statement applies to the related information included within the scope of work described below. The data presented in Amgen’s 2011 Environmental Sustainability Report is the sole responsibility of the management of Amgen. Bureau Veritas was not involved in the drafting of the Report. Our sole responsibility was to provide independent verification of the accuracy of selected information included in the report. Scope of work Amgen requested Bureau Veritas to verify the accuracy of the following environmental health and safety data summarized in Amgen’s Environmental Sustainability Report for the Calendar Year 2011 reporting period:  Energy Use (Total, Direct and Indirect)  Carbon Dioxide (CO2) emissions (Direct Scope 1 and Indirect Scope 2)  Water Withdrawal and Fate  Waste Quantities and Disposition  Fleet Fuel Efficiency  Health and Safety Data including Injury and Illness Rate, Lost Day Rate and Severity Rate  Number of Environmental Violations Excluded from the scope of our work is any verification of information relating to:  Text or other written statements associated with Amgen’s 2011 Environmental Sustainability Report  Activities outside the defined verification period of Calendar Year 2011 Methodology As part of its independent verification, Bureau Veritas undertook the following activities: 1. Interviews with relevant personnel of Amgen regarding data collection and reporting systems; 2. Review of Amgen’s data and information systems and methodology for collection, aggregation, analysis and internal audit of information used to determine the environmental data; 3. Review of documentary evidence produced by Amgen; and 4. Audit of Amgen’s data traced back to the source during site visits to Amgen’s facilities in Longmont, Colorado; Boulder, Colorado; and Thousand Oaks, California. Our work was conducted against Bureau Veritas’ standard internal procedures and guidelines for external verification/assurance of sustainability reports, based on current practice in independent assurance and the principles of ISO 14064-3: Greenhouse gases -- Part 3: Specification with guidance for the validation and verification of greenhouse gas assertions. The work was planned and carried out to provide limited verification and we believe it provides an appropriate basis for our conclusions.
  • 18. 2011 Environmental Sustainability Report Summary of Data — Assurance Amgen Page 2 Our findings On the basis of our methodology and the activities described above:  Nothing has come to our attention to indicate that the reviewed information within the scope of our verification is not materially correct.  Nothing has come to our attention to indicate that the reviewed information is not a fair representation of the actual environmental health and safety data for calendar year 2011.  It is our opinion that Amgen has established appropriate systems for the collection, aggregation and analysis of quantitative data, including energy use, direct and indirect CO2 emissions, water withdrawal and fate, waste quantities and disposition, fleet fuel efficiency, injury and illness rates, lost day case rate, severity and number of environmental violations. Statement of independence, impartiality and competence Bureau Veritas is an independent professional services company that specializes in Quality, Health, Safety, Social and Environmental management with almost 180 years of history in providing independent assurance services, and an annual 2010 revenue of 3.3 Billion Euros. No member of the verification team has a business relationship with Amgen, its Directors or Managers beyond that required of this assignment. We have conducted this verification independently, and there has been no conflict of interest. Bureau Veritas has implemented a Code of Ethics across the business to maintain high ethical standards among staff in their day to day business activities. Attestation: David C. Reilly, Lead Verifier Lisa S. Barnes, Technical Reviewer Project Manager Technical Director, Climate Change Services Bureau Veritas North America, Inc. Bureau Veritas North America, Inc. Costa Mesa, California Denver, Colorado April 11, 2012
  • 19. “Environmental sustainability makes good business sense; it’s an important investment in our future.”—K­ evin Sharer, Chairman and CEO, Amgen Robert Bradway, President and COO, Amgen 9
  • 20. For more information about environmental sustainabilityat Amgen, visit environment.amgen.com.We welcome your feedback at esfeedback@amgen.com.Amgen Inc.One Amgen Center DriveThousand Oaks, CA 91320-1799www.amgen.com© 2012 Amgen Inc. All rights reserved.

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