SIMS in Combinatorial Chemistry An optical image of a bead-holder specially fabricated for 60 m polystyrene beads (capacity: 10,000 beads/cm 2 ) The TOF image of Sasrin-Biotin beads loaded into the bead-holder. The molecular mass of biotin 245.3 amu is shown in green. R. M. Braun, A. Beyder, J. Xu, M. C. Wood, A. G. Ewing and N. Winograd, Anal. Chem. 71, 3318 (1999).
ARTOF-SIMS Sample Manipulator a) Azimuthal Rotation: Sample rotates like the hands of a clock, around the center of the crystal. b) Polar Rotation: Sample rotates like a revolving door, around the axis perpendicular to the azimuthal axis.
CD 3 S-Cu (100): The Model System 1) Chemisorption to a four-fold hollow 3) No domains 2) No tilt angle due to short R group 4) Simplified mass spectra Imanishi, S. Takenaka, T. Yokoyama, Y. Kitajima and T.Ohta J. PHYS. IV FRANCE 7 (1997)
FCC (100) Surface 1) Red atom is an ejecting atom 2) Blue atoms are blocking atoms 3) SIMS yield decreases with blocking