Pyrethrum and synthetic pyrethroids

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Pyrethrum and synthetic pyrethroids

  1. 1. INTRODUCTION
  2. 2. WHAT IS PYRETHRUM?
  3. 3. PROPERTIES Ecofriendly Quick action Low toxicity Multipurpose √ Repellant √ Flushing agent No development of insect immunity
  4. 4. MECHANISM OF ACTION
  5. 5. METHOD OF APPLICATION  Space spray  Kills adult mosquitoes & other insects  0.5 – 1 oz of solution/1000 cu ft of space  After spraying windows & doors should be closed for not less than 30 mins
  6. 6. SYNERGESTIC EFFECT?? Pyrethrum + DDT or Piperonyl (low toxicity) butoxide Common formulation of PYRETHRIN (Enhanced toxicity)
  7. 7. SYNTHETIC PYRETHROIDS Replace the natural pyrethrins 10 times more effective Examples: 1) Lambda cyhalothrin(cyano group) 2) Permethrin 3) Tetramethrin 4) Rosethrin 5) Proparthin
  8. 8. MECHANISM OF ACTION Affect CNS Prolong deactivation of voltage gated Na channel Prolonged excitation of fibres Lambda cyhalothrin-more neurotoxic -more selectivity
  9. 9. SIDE EFFECTSPYRETHROIDS Inhalation- coughing,wheezing,shortness of breath Skin- itching,rash,paraesthesia(lamda cyhalothrin) Neurotoxic effect-tremor, incoordination, increased body temp Long term effects-disrupt endocrine system -carcinogen(thyroid gland)
  10. 10. PIPERONYL BUTOXIDE Skin ulceration Eye irritation Long term-carcinogen
  11. 11. THANK YOU

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