Retroviruses

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Retroviruses:
http://microbiologybytes.wordpress.com/

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Retroviruses

  1. 1. Retroviruses
  2. 2. Structure
  3. 3. Genomes
  4. 4. Replication
  5. 5. Integration
  6. 6. Gene Expression
  7. 7. Genetics
  8. 8. So what have retroviruses ever done for us? Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis Nature 403: 785-9
  9. 9. Pathogenesis <ul><li>Paralysis </li></ul><ul><li>Wasting </li></ul><ul><li>Ataxia </li></ul><ul><li>Arthritis </li></ul><ul><li>Dementia </li></ul><ul><li>Neuropathy </li></ul><ul><li>Transformation </li></ul><ul><li>Immunodeficiency </li></ul>
  10. 10. Summary Retroviruses have been studied intensively for over 100 years as causes of disease and more recently as gene vectors. For more information, see: MicrobiologyBytes

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