You are interested in evaluating the benefits and harms associated with the use of thrombectomy devices in acute coronary syndromes. You need to determine what literature is available to conduct your review.
Your due diligence pays off. You now realize that your initial search “thrombectomy AND acute coronary syndrome” would compromise the recall. Using “((Thrombectomy OR MerciClot.mp OR “other devices names”) AND (acute coronary syndromes OR myocardial infarction OR angina, unstable))” would assure better recall without appreciably impacting precision.
You decide to search the U.S. Food and Drug Administration Web site and ClinicalTrials.gov to identify studies that might be appropriate for your systematic review. These Web sites are sources of what kind of documents?
You conduct a thorough search of MEDLINE and Cochrane Central, use two searches (one for “benefits” and another for “harms”), and employ targeted hand searching and grey literature evaluation. What is the last thing you need to remember to do that is germane to searching?
Choose only citations that agree with your preconceived notions.
Selectively report aspects of your search strategy.
Provide transparent reporting of search strategies and the citations you identified.
This quiz was p repared by C. Michael White, Pharm.D., FCP, FCCP, a member of the University of Connecticut/Hartford Hospital Evidence-based Practice Center.
T his module is based on chapter 5 in version 1.0 of the Methods Reference Guide for Effectiveness and Comparative Effectiveness Reviews (available at: http://effectivehealthcare.ahrq.gov/repFiles/ 2007_10Draft MethodsGuide.pdf) .