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Submitted to

Mr.P.Yonatansir

Associate professer

Jgcollege of nursing

Ahmedabad              Submitted by

                             MrsHeena Mehta

                             S.Y.M.Sc Nursing
Jg college of nursing

                                      Ahmedabad

Sub-Medical Surgical Nursing

Topic- Basal cell carcinoma of face

Submitted to-Mr.P.Yonatansir

Submitted by-MrsHeena Mehta

Sr no                                    content              Page no
1        Identification data
2        History
3        Physical examination
4        Investigation
5        Disease condition
6        Definition
7        Pathophysiology
8        Management
9        Nursing diagnosis
10       Health teaching
11       Bibliography
IDENTIFICATION DATA
PATIENT’S NAME: JivatibenBhojabhaiGajjar

Indoor.no: F 56854

AGE:64 years

SEX:Female

DATE OF ADMISSION`:12-1-2012

DR’S UNIT: Unit-2 Dr.prakashpatel

WARD: cancer female medical ward

MARRITAL STATUS: married

RELIGION: Hindu

EDUCATION: Illiterate                    .

OCCUPATION: House wife

ADDRESS:Jetpur,Rajkot

DIAGNOSIS:Basal cell carcinoma of the face

HEIGHT: 146Cm

WEIGHT: 5 Kg
PRESENTING COMPLAINS:
Patient having complained of following:

-Fever

-Itching on face

-Black ulcer on the face

-Dryness of face skin

-Indigesion

-Weakness

PRESENT HISTORY:

Jivatiben has complain of the dryness of the face skin, itching of the face , black ulcer on the
face, loss of apitite and weakness since last 8 month so she has to gone for treatment at
private hospital in Jetpur (Rajkot) but symptoms not relieve itching constant occure than she
refer to the civil hospital for medication.

PAST HISTORY:

PAST MEDICAL HISTORY:

Upto 64 year she has lot off time taken medication for minor disease but not need any
hospitalization ,symptomatic medication taken for three to five day and symptoms relieve
but last 8 month she was suffering from the skin disease and symptoms not relieve thus refer
civil hospital and finally after total investigation she diagnose BASAL CELL CARCINOMA
OF THE FACE and admit in the civil hospital for treatment.

PAST SURGICAL HISTORY:

No any surgical treatment needed Jivatiben, No any surgery done to the Jivatiben.

DIET HISTORY:




Jivatiben taken normal diet in her life. She has a farm so her husband grow
normaly all types of vegetables in his farm .


PERSONAL HISTORY:
      Diet : vegetarian & taking all type of small amount diet
      Appetite : Decreased
      Sleep :disturb
      Micturation : No burning micturation
      Bowel habit: Abnormal habits
      Smoking : No
      Alcohol : No
      Drugs : No
      Tobacco : No
      No any other habits

FAMILY HISTORY:
In her family no any family members have history of any Hypertension, Diabetes mellitus,
Ischemic heart disease, Epilepsy, Asthma, Storks, Arthritis, Cancer or any other disease. Her
father suffering from the tuberculosis and expired with this disease.

Sr.    Name of Family      Age in Relationship
                                                     Education      Occupation
No.      Members           Year With patient

 1    BhojabhaiBudhabh 7oYrs.          Husband        Illiterated     Farmer
aiGajjar

 2     JivatibenGajjar      64Yrs    Patient          Illiterated    Housewife

 3     JentibhaiGajjar      46Yrs   Son                 8th pass       Farmer

 4     NandubenGajjar       40Yrs   Son’s wife          7th pass     Housewife

 5     Ramesh Gajjar        20Yrs    Grand son         12th pass    Farmer

 6     Neeta Gajjar           Yrs   Grand                 10th            -
                                    daughter

 7     RasikGajjar          25      son                 B.Com             -

 8     NanjiGajjar          20      son                 B.Com             -



SOCIOECONOMIC HISTORY:
In Jivatiben’s house , her husband and elderson as a farmer so they work in farm and grow
seasional vegetables and cereals for family and for sale so her income is not fix sometime her
family earn more money and some times her family earn less money.

PHYSICAL EXAMINATION:
VITAL SIGN

Date         Temp      ( Pulse        Respiration(/min) BP (mm of
             F)          (/min)                         Hg)
16-07-       100 F       100/min      20/min            118/74
2012
17-07- 99 F   126/min                 24 min             122/64
2012
18-07- 99 F   120/min                 26 min             114/78
2012
19-07- 98.6F  116/min                 20 min             120/74
2012
GENERAL OBSERVATION:

          Sensorium: She is conscious and well oriented
          Foul body odour: no any bad odour from her body
          Foul breath : no
          Posture : normal
          Hair: Brown hair, clean no any dandruff.
GENERAL APPERANCE:

       Body image: normal
       Health: Unhealthy
       Activity: less active

MENTAL STATUS:

Consciousness: conscious

       Look: weakness, fatigue due to her disease.

Posture

       Body curves: normal
       Movement: Full movement(if given deep pain than small reflection was done by
       patient)


Height: 146cm                                 Weight: 67kg

SKIN CONDITION:

       Color: pallor
       Texture: Rough skin
       Temperature: warm
       Lesions: no lesions present

HEAD & FACE:

       Scalp: clean
       Face: pale, fatigue, fear, anxiety

EYES:

       Eyebrow: normal
       Eye lashes: no infection, not open by patient
       Eyelids: no any injury or oedema is present
       Eye balls: not sunken
       Conjunctiva: pale
       Sclera: no jaundiced
       Pupils: constricted
       Vision: react to light

EAR:

       External ear: no discharge present
Hearing: normal

NOSE:

      External nares: Redness present
      Nostrils: normal. keeping face mask for proper oxygenation

MOUTH & PHARYNX:
   Lips: dry
   odour of the mouth: not present
   Teeth: normal
   Mucus membrane: dry
   Tongue: pale and moist

NECK:

      Lymph node: Not palpable
      Thyroid gland: normal
      Range of motion: flexion, extension and rotation when done by someone, patient able
      to done by own self.

CHEST:

      Thorax: expansion
      Breath sound: No any sound heard
      Heart: normal

ABDOMEN:

      Observation: no skin rashes and scar
      Auscultation: reduced bowel sound
      Palpation: no tenderness present

Percussion: not presence of gas, fluid or masses

EXTREMITIES:

      Lower extremities: fully movements of lower extremities. mildoedema present
      Upper extremities: can move both hands but mild oedema is present

Genital and rectum:

      No enlarged inguinal lymph nodes, No hemorrhoids, no enlargement of prostate
      glands.
      Bladder & Bowel Pattern: Abnormal.
INVESTIGATION:
Serum Biochemistry test:
       Investigation                 In patient         Normal value

Hemoglobin                      12 % gm%           14 – 17 gm %.
RBC                             100 mg/dl          153mg/ml
UREA                            24mg/dl            15-45mg/dl
WBC                             9,200/cumm         4000-11000/cumm
S.creat.                        0.59mg/dl          0.7-1.5mg/dl
SGPT                            36U/L              0-55U/L
S. phosphate                    108 U/L            <50-150U/L
S.Billirubin                    0.7mg/dl           0.2-1.2mg/dl


BLOOD CHEMISTERY
FASTING                         90.0mg/ dl         70-110mg/dl
CHOLESTROL                      174 mg/dl          >240.0mg/dl



Serum Electrolytes:

     Investigation              In patient              Normal value
S. Na+                    144.3 meq/L              135-145meq/L
S.K+                      4.62 meq/L               3.5-5.5 meq/L
Chloride                  105                      97-108
X-RAY CHEST:

            Olcg in bothlungs

ECG:wnl

MEDICATION

CHEMOTHERAPY GIVEN AFTER SURGERY

-Injection 5FU and cyclophosphamide regimen every 3week for three cycle.

-Injection amikasine 500gm i/v 12hourly.

-Injection voveran 1 ampoule i/v 12hourly.

- Injection Ondensten 1 ampoule i/v sos

- Tablet-Rantac 150 mg 1 bd.

-Tablet- MV/BC 1 bd
Maintain intake and output chart daily
      Contineus observation of the patient on monitor for any abnormal symptoms.
      TPR chart 1 hourly Monitoring continuously for blood pressure, respiration rate,
      pulse, and for oxygen saturation.
      Care taken of catheter daily
      Care taken of all tubes which are inserted
      Watched for respiratory failure .
      Changed the dressing and adhesive tap at the site of intracath.




      DISEASE CONDITION
ANATOMY AND PHYSIOLOGY OF SKIN-




The skinis the largest organ in the body, comprising about 15% of the body weight. The
total skin surface of an adult ranges from 12 to 20 square feet. In terms of chemical
composition, the skin is about 70% water, 25% protein and 2% lipids. The remainder
includes trace minerals, nucleic acids, glycosoaminoglycans, proteoglycans and numerous
other chemicals.
The skin consists of three main layers: epidermis, dermis and subcaneous tissue.
The Epidermis
The epidermis is the topmost layer of the skin. It is the first barrier between you and the
outside world. The epidermis consists of three types of cells keratinocytes, melanocytes and
Langerhans cells. Keratinocytes, the cells that make the protien keratin, are the predominant
type of cells in the epidermis. The total thinkness of the epidermis is usually about 0.5 - 1
mm. At the lowermost portion of the epidermis are immature, rapidly dividing
keratinocytes. As they mature, keratinocytes lose water, flatten out and move upward.
Eventually, at the end of their life cylce, they reach the uppermost layer of the epidermis
called stratum corneum. Stratum corneum consists mainly of dead keratinocytes, hardened
proteins (keratins) and lipids, forming a protective crust. Dead cells from stratum corneum
continuously slough off and are replaced by new ones coming from below. The skin
completely renews itself every 3 - 5 weeks. Most mild peels work by partly removing the
stratum corneum and thus speeding up skin renewal.
Another significant group of cell in the epidermis are melanocytes, the cells producing
melanin, the pigment responsible for skin tone and color. Finally, Langerhans cells are
essentially a forepost of the immune system in the epidermis. They prevent unwanted
foreingn substances from penetrating the skin.
The condition of epdermis determines how "fresh" your skin looks and also how well your
skin absorbs and holds moisture. Wrinkles, however, are formed in lower layers.
The Dermis
The dermis is the middle layer of the skin located between the epidermis and subcutaneous
tissue. It is the thickest of the skin layers and comprises a tight, sturdy mesh of collagen and
elastrin fibers. Both collagen and elastin are critically important skin proteins: collagen is
responsible for the structural support and elastin for the resilience of the skin. The key type
of cells in the dermis is fibroblasts, which synthesize collagen, elastin and other structural
molecules. The proper function of fibroblasts is highly important for overall skin health.
The dermis also contains capillaries (tiny blood vessels) and lymph nodes (depots of
immune cells). The former are important for oxygenating and nourishing the skin, and the
latter -- for protecting it from invading microorganisms.
Finally, the dermis contains sebacious glands, sweat glands, hair follicles as well as a
relatively small number of nerve and muscle sells. Sebacious glands, located around hair
follicles, are of particular importance for skin health as they produce sebum, an oily
protective substance that lubricates and waterproofs the skin and hair. When sebacious
gland produce too little sebum, as is common in older people, the skin becomes excessively
dry and more prone to wrinkling. Conversely, overproduction or improper composition of
sebum, as is common in adolescents, often leads to acne.
The dermis is the layer responsible for the skin's structural integrity, elasticity and
resilience. Wrinkles arise and develop in the dermis. Therefore, an anti-wrinkle treatement
has a chance to succeed only if it can reach as deep as the dermis. Typical collagen and
elastin creams, for example, never reach the dermis because collagen and elastin molecules
are too large to penetrate the epidermis. Hence, contrary to what some manufacturers of
such creams might imply, these creams have little effect on skin wrinkles.
Subcutaneous tissue
Subcutanous (hypodermis) tissue is the innermost layer of the skin located under the dermis
and consisting mainly of fat. The predominant type of cells in the subcutaneous tissue is
adipocytes or fat cells. Subcutaneous fat acts as a shock absorber and heat insulator,
protecting underlying tissues from cold and mechanical trauma. Interestingly, most
mammals lack subcutaneous tissue because their fur serves as a shock absorber and heat
insulator. Sweat glands and minute muscles attached to hair follicles originate in
subcutaneous tissue.
The loss of subcutaneous tissue, often occurring with age, leads to facial sag and
accentuates wrinkles. A common procedure performed by dermatologists to counteract this
process is to inject fat (collected elsewhere in the body) under the wrinkles on the face .




DEFINITION:Basal cell carcinoma is the most common form of cancer worldwide and
accounts for about 80% of all cases of skin cancer.



CAUSES:

In Book                                                       In Patient
Radiation expose, UV Rays                                     no
Gene Maturations                                              May be
Arsenic exposure through ingestion                            no


Immunosuppression                                             May be

Xerodermapigmentosum                                          May be

Epidermodysplasticverruciformis                               no

Nevoid basal cell carcinoma syndrome                          No

Bazex syndrome                                                No

Previous nonmelanoma skin cancer                              no

Rombo syndrome                                                No

Alcohol consumption                                           no
Types of basal cell carcinoma of the skin

In Book                                            In My Patient

Nodular: About 60% of BCCs are nodular.            There is small nodes seen over the face.
They start out as flat, well-defined lesions,
then often become small bumps, which
eventually collapse in the middle, leaving a
raised ring on the border. Most nodular
BCCs are on the face and so can be
disfiguring if not treated promptly.

Pigmented: Pigmented BCCs are similar to           There is Black pigmentation seen over nodes
the nodular type, but they can have brown or
black spots in them. They can be confused
with some types of melanoma.

Fibrosing or Sclerotic: These BCCs are
usually found on the face and look similar to
scars. They are usually firm, ill-defined at the
border, flat or slightly depressed, yellowish
in color, and the surface tends to be smooth
and shiny.

Superficial: This type comprises about 15%
of BCCs. They spread outward from a red,
well-defined, scaly patch, most commonly
found on the trunk and limbs. They are easily
confused with psoriasis or eczema.

Fibroepithelioma of Pinkus: This is a rare
type of BCC. It tends to be a smooth,
elevated, small nodule found on the back,
extremities, groin, or sole of the foot. As
those are not sun-exposed areas, this disease
is probably not sun-related.


PATHOPHYSIOLOGY:

Over exposure to sun leads to the formation of thymine dimers, a form of DNA damage.
cumulative DNA damage leading to mutations.



Apart from the mutagenesis, over exposure to sunlight depresses the local immune system,



Basal-cell carcinoma also develops as a result of Basal-Cell Nevus Syndrome,



Developed tumors of the jaw, palmar or plantar (sole of the foot) pits, calcification of
the falxcerebri (in the center line of the brain) and rib abnormalities.




which inhibits the hedgehog signaling pathway.



A mutation in the SMO gene, which is also on the hedgehog pathway, also causes basal-cell
carcinoma

CLINICAL MENIFESTATION:

In Book                                         In Patient
                                                Present
skin bump or growth that is:

  Pearly or waxy
  White or light pink
  Flesh-colored or brown


A skin sore that bleeds easily           Present
A sore that does not heal                Present
Oozing or crusting spots in a sore         Not Present
Appearance of a scar-like sore without   Present
having injured the area
Irregular blood vessels in or around the Not Present
spot
A sore with a depressed (sunken) area in Not Present
the middle
ASSESSMENT & DIAGNOSTIC FINDINGS:
IN BOOK                                    IN PATIENT
   - Taking a thorough history                - Done
      including family history
   - Physical examination (note BP           - Done
      & weight)
   - Laboratory work (cholesterol            - Done
      levels, glucose )
      skin biopsy                            - Done
  Shave biopsy uses a thin surgical
  blade to shave off the top layers of
  skin. This is the most common
  method for diagnosing BCC.
  Punch biopsy uses a round, cookie
  cutter-like tool. It is used to take a
  deeper skin sample.



MANAGEMENT:

  Curettage and electrodessication
  Surgical excision (removal)
  Mohs surgery (also known as "micrographic surgery"), especially if the lesion is on the
  face, is recurrent, has a diameter of greater than 2 cm, or is the sclerotic type
  Topical creams such as imiquimod is FDA-approved for the treatment of superficial BCCs
  not on the face, although studies have shown it can be effective against nodular BCC as
  well

      Excision
      Simple surgical excision (removal) is used to treat both primary and recurrent tumors.
      The procedure involves surgically removing the tumor and a certain amount of
      normal-appearing skin surrounding it (the "margin"): For basal cell and squamous cell
      carcinomas, margins are often 2 to 4 mm. The cure rates following excision are 95%
      and 92% for primary BCC and SCC, respectively, and are dependent on the site, size,
      and pattern of the tumor. Excision may be performed in the outpatient or inpatient
      setting depending on the extent of the cancer.

      Topical Creams
      Since its approval in 2004, the immune systemactivator imiquimod (also known by the
      brand nameAldara) has been a commonly prescribed topical (skin only) cream for
      small superficial and nodular basal cell carcinomas, as well as a pre-cancerous
      condition called actinic keratosis. It is spread on the lesion five times per week,
      usually for six weeks, and completely clears the skin in about 88% of patients or more,
      depending on the exact type of cancer. Another cream for superficial BCC is 5-
      flourouracil (Carac or Efudex), a chemotherapy drug that is also used intravenously.
      These treatments usually don't leave any scars, but they can cause considerable pain
      and swelling as they work. Several other creams are being tested now,
including ingenolmebutate(PEP005), which is derived from a plant called the "petty
     spurge."

     Curettage and Electrodesiccation
     Curettage and electrodesiccationis a simple, quick and effective method for destroying
     small basal cell and squamous cell carcinomas. After scraping away the growth with a
     long spoon-like instrument called a curette, the physician uses a mild electric current
     to destroy any remaining abnormal cells. This scraping and cauterizing process is
     typically repeated three times, and the wound tends to heal without stitches. It is best
     for primary, not recurrent, lesions. The cure rates depend on the site: high-risk
     locations (nose, ear, chin, mouth) have a recurrence rate of 4% to 18%, depending on
     the tumor size. Recurrence rates decrease to 3% for tumors at low-risk sites of the
     trunk and extremities. Overall, the 5-year cure rates for primary BCC and SCC treated
     with C and E are 92% and 96%, respectively.

     Mohs Surgery
     TheMohs procedure (also known as Mohs micrographic surgery or margin controlled
     excision) is an advanced technique developed in the 1940s by Dr. Frederic E. Mohsfor
     removing lesions due to basal or squamous cell carcinoma. It involves removing thin
     sections of the skin growth, layer by layer. Each layer is then examined under the
     microscope, and removal of layers continues until no cancerous cells remain. It has the
     highest cure rate of any skin cancer treatment and doesn't cause as much scarring as
     other methods. It is especially useful for treating recurring skin cancer, larger tumors,
     tumors on the ear, eyelid, nose, lip, or hand, tumors in sites prone to recurrence, and
     the sclerotic subtype of basal cell carcinoma. It is the "gold standard" treatment: The
     5-year recurrence rate is 1% for BCC and 3% for SCC. However, it is more costly,
     time-consuming, and labor-intensive than other methods.

MEDICAL MANAGEMENT:

 - Chemotherapy in four cycle with Adreamycine andcyclophosphemide.
 - Analgesics
 - Antibiotics
NURSING MANAGEMENT:

  - Identify at risk patients, & teach lifestyle modifications to prevent development any
    complication.
  - Teach patient to control cholesterol levels through dietary reduction of cholesterol
    intake, exercise, smoking cessation.
  - Note & report findings from history, physical examination, & laboratory results that
    indicate hypertension or diabetes, &teach to control blood pressure by taking
    treatment in the nearest hospital.



NURSING DIAGNOSIS:
1.   Risk for infection related to decrease immune system.
   2.   Altered body temperature due to presence of infection.
   3.   Imbalance nutritional level less than body requirement related to loss of appetite.
   4.   Activity intolerance related to disease.

   5 Impaired body image due disease.

 6 Altered self image and confidence due to fegure.




 HEALTH TEACHING:


        Explain patient’s relatives about discharge planning.
        Give advice about regular medication as per timing.
        Advice given about good nutritive diet.
        Advice given for prevention of infection management.


Prevention

The best way to prevent skin cancer is to reduce your exposure to sunlight. Ultraviolet light
is most intense at midday, so try to avoid sun exposure during these hours. Protect the skin
by wearing hats, long-sleeved shirts, long skirts, or pants.

Always use sunscreen:

  Apply high-quality sunscreens with SPF (sun protection factor) ratings of at least 15.
  Look for sunscreens that block both UVA and UVB light.
  Apply sunscreen at least 30 minutes before going outside, and reapply it frequently.
  Use sunscreen in winter, too.


Possible Complications

Untreated, basal cell cancer can spread to nearby tissues or structures, causing damage.
This is most worrisome around the nose, eyes, and ears.



Explain about follow up care.
BIBLIOGRAPHY:

  1. Bennette and Plum; “TEXTBOOK OF MEDITION ; 10thedition, 1996;
         W.B. Saunders Company, New York : 1996. PP :

  2. Black J.M; “MEDICAL SURGICAL NURSING; 5th edition, 1999
     ; W.B. Saunders Company, Philadelphia. PP:

  3. Brunners&Suddarth’s; “TEXT BOOK OF MEDICAL SURGICAL
     NURSING VOL-_1”;10th edition, 2004; Elsevier Publishers, New Delhi,
     India. PP:

   4. B T Basavanthappa;”TEXT BOOK OF NURSING           THEORIES”,Jaypee brothers
      Medical Publishers ,New Delhi.
PP: 40-
     WEBSITES:
          - http://www.wikipedia.com.
          - http://www.patho.skindisease.org/.com.in
          - http://www.google.com.
             - http://www.medicine.com.

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Case presentation of basal cell carcinoma of face no 4

  • 1. Submitted to Mr.P.Yonatansir Associate professer Jgcollege of nursing Ahmedabad Submitted by MrsHeena Mehta S.Y.M.Sc Nursing
  • 2. Jg college of nursing Ahmedabad Sub-Medical Surgical Nursing Topic- Basal cell carcinoma of face Submitted to-Mr.P.Yonatansir Submitted by-MrsHeena Mehta Sr no content Page no 1 Identification data 2 History 3 Physical examination 4 Investigation 5 Disease condition 6 Definition 7 Pathophysiology 8 Management 9 Nursing diagnosis 10 Health teaching 11 Bibliography
  • 3. IDENTIFICATION DATA PATIENT’S NAME: JivatibenBhojabhaiGajjar Indoor.no: F 56854 AGE:64 years SEX:Female DATE OF ADMISSION`:12-1-2012 DR’S UNIT: Unit-2 Dr.prakashpatel WARD: cancer female medical ward MARRITAL STATUS: married RELIGION: Hindu EDUCATION: Illiterate . OCCUPATION: House wife ADDRESS:Jetpur,Rajkot DIAGNOSIS:Basal cell carcinoma of the face HEIGHT: 146Cm WEIGHT: 5 Kg
  • 4. PRESENTING COMPLAINS: Patient having complained of following: -Fever -Itching on face -Black ulcer on the face -Dryness of face skin -Indigesion -Weakness PRESENT HISTORY: Jivatiben has complain of the dryness of the face skin, itching of the face , black ulcer on the face, loss of apitite and weakness since last 8 month so she has to gone for treatment at private hospital in Jetpur (Rajkot) but symptoms not relieve itching constant occure than she refer to the civil hospital for medication. PAST HISTORY: PAST MEDICAL HISTORY: Upto 64 year she has lot off time taken medication for minor disease but not need any hospitalization ,symptomatic medication taken for three to five day and symptoms relieve but last 8 month she was suffering from the skin disease and symptoms not relieve thus refer
  • 5. civil hospital and finally after total investigation she diagnose BASAL CELL CARCINOMA OF THE FACE and admit in the civil hospital for treatment. PAST SURGICAL HISTORY: No any surgical treatment needed Jivatiben, No any surgery done to the Jivatiben. DIET HISTORY: Jivatiben taken normal diet in her life. She has a farm so her husband grow normaly all types of vegetables in his farm . PERSONAL HISTORY: Diet : vegetarian & taking all type of small amount diet Appetite : Decreased Sleep :disturb Micturation : No burning micturation Bowel habit: Abnormal habits Smoking : No Alcohol : No Drugs : No Tobacco : No No any other habits FAMILY HISTORY: In her family no any family members have history of any Hypertension, Diabetes mellitus, Ischemic heart disease, Epilepsy, Asthma, Storks, Arthritis, Cancer or any other disease. Her father suffering from the tuberculosis and expired with this disease. Sr. Name of Family Age in Relationship Education Occupation No. Members Year With patient 1 BhojabhaiBudhabh 7oYrs. Husband Illiterated Farmer
  • 6. aiGajjar 2 JivatibenGajjar 64Yrs Patient Illiterated Housewife 3 JentibhaiGajjar 46Yrs Son 8th pass Farmer 4 NandubenGajjar 40Yrs Son’s wife 7th pass Housewife 5 Ramesh Gajjar 20Yrs Grand son 12th pass Farmer 6 Neeta Gajjar Yrs Grand 10th - daughter 7 RasikGajjar 25 son B.Com - 8 NanjiGajjar 20 son B.Com - SOCIOECONOMIC HISTORY: In Jivatiben’s house , her husband and elderson as a farmer so they work in farm and grow seasional vegetables and cereals for family and for sale so her income is not fix sometime her family earn more money and some times her family earn less money. PHYSICAL EXAMINATION: VITAL SIGN Date Temp ( Pulse Respiration(/min) BP (mm of F) (/min) Hg) 16-07- 100 F 100/min 20/min 118/74 2012 17-07- 99 F 126/min 24 min 122/64 2012 18-07- 99 F 120/min 26 min 114/78 2012 19-07- 98.6F 116/min 20 min 120/74 2012 GENERAL OBSERVATION: Sensorium: She is conscious and well oriented Foul body odour: no any bad odour from her body Foul breath : no Posture : normal Hair: Brown hair, clean no any dandruff.
  • 7. GENERAL APPERANCE: Body image: normal Health: Unhealthy Activity: less active MENTAL STATUS: Consciousness: conscious Look: weakness, fatigue due to her disease. Posture Body curves: normal Movement: Full movement(if given deep pain than small reflection was done by patient) Height: 146cm Weight: 67kg SKIN CONDITION: Color: pallor Texture: Rough skin Temperature: warm Lesions: no lesions present HEAD & FACE: Scalp: clean Face: pale, fatigue, fear, anxiety EYES: Eyebrow: normal Eye lashes: no infection, not open by patient Eyelids: no any injury or oedema is present Eye balls: not sunken Conjunctiva: pale Sclera: no jaundiced Pupils: constricted Vision: react to light EAR: External ear: no discharge present
  • 8. Hearing: normal NOSE: External nares: Redness present Nostrils: normal. keeping face mask for proper oxygenation MOUTH & PHARYNX: Lips: dry odour of the mouth: not present Teeth: normal Mucus membrane: dry Tongue: pale and moist NECK: Lymph node: Not palpable Thyroid gland: normal Range of motion: flexion, extension and rotation when done by someone, patient able to done by own self. CHEST: Thorax: expansion Breath sound: No any sound heard Heart: normal ABDOMEN: Observation: no skin rashes and scar Auscultation: reduced bowel sound Palpation: no tenderness present Percussion: not presence of gas, fluid or masses EXTREMITIES: Lower extremities: fully movements of lower extremities. mildoedema present Upper extremities: can move both hands but mild oedema is present Genital and rectum: No enlarged inguinal lymph nodes, No hemorrhoids, no enlargement of prostate glands. Bladder & Bowel Pattern: Abnormal.
  • 9. INVESTIGATION: Serum Biochemistry test: Investigation In patient Normal value Hemoglobin 12 % gm% 14 – 17 gm %. RBC 100 mg/dl 153mg/ml UREA 24mg/dl 15-45mg/dl WBC 9,200/cumm 4000-11000/cumm S.creat. 0.59mg/dl 0.7-1.5mg/dl SGPT 36U/L 0-55U/L S. phosphate 108 U/L <50-150U/L S.Billirubin 0.7mg/dl 0.2-1.2mg/dl BLOOD CHEMISTERY FASTING 90.0mg/ dl 70-110mg/dl CHOLESTROL 174 mg/dl >240.0mg/dl Serum Electrolytes: Investigation In patient Normal value S. Na+ 144.3 meq/L 135-145meq/L S.K+ 4.62 meq/L 3.5-5.5 meq/L Chloride 105 97-108 X-RAY CHEST: Olcg in bothlungs ECG:wnl MEDICATION CHEMOTHERAPY GIVEN AFTER SURGERY -Injection 5FU and cyclophosphamide regimen every 3week for three cycle. -Injection amikasine 500gm i/v 12hourly. -Injection voveran 1 ampoule i/v 12hourly. - Injection Ondensten 1 ampoule i/v sos - Tablet-Rantac 150 mg 1 bd. -Tablet- MV/BC 1 bd
  • 10. Maintain intake and output chart daily Contineus observation of the patient on monitor for any abnormal symptoms. TPR chart 1 hourly Monitoring continuously for blood pressure, respiration rate, pulse, and for oxygen saturation. Care taken of catheter daily Care taken of all tubes which are inserted Watched for respiratory failure . Changed the dressing and adhesive tap at the site of intracath. DISEASE CONDITION ANATOMY AND PHYSIOLOGY OF SKIN- The skinis the largest organ in the body, comprising about 15% of the body weight. The total skin surface of an adult ranges from 12 to 20 square feet. In terms of chemical composition, the skin is about 70% water, 25% protein and 2% lipids. The remainder includes trace minerals, nucleic acids, glycosoaminoglycans, proteoglycans and numerous other chemicals.
  • 11. The skin consists of three main layers: epidermis, dermis and subcaneous tissue. The Epidermis The epidermis is the topmost layer of the skin. It is the first barrier between you and the outside world. The epidermis consists of three types of cells keratinocytes, melanocytes and Langerhans cells. Keratinocytes, the cells that make the protien keratin, are the predominant type of cells in the epidermis. The total thinkness of the epidermis is usually about 0.5 - 1 mm. At the lowermost portion of the epidermis are immature, rapidly dividing keratinocytes. As they mature, keratinocytes lose water, flatten out and move upward. Eventually, at the end of their life cylce, they reach the uppermost layer of the epidermis called stratum corneum. Stratum corneum consists mainly of dead keratinocytes, hardened proteins (keratins) and lipids, forming a protective crust. Dead cells from stratum corneum continuously slough off and are replaced by new ones coming from below. The skin completely renews itself every 3 - 5 weeks. Most mild peels work by partly removing the stratum corneum and thus speeding up skin renewal. Another significant group of cell in the epidermis are melanocytes, the cells producing melanin, the pigment responsible for skin tone and color. Finally, Langerhans cells are essentially a forepost of the immune system in the epidermis. They prevent unwanted foreingn substances from penetrating the skin. The condition of epdermis determines how "fresh" your skin looks and also how well your skin absorbs and holds moisture. Wrinkles, however, are formed in lower layers. The Dermis The dermis is the middle layer of the skin located between the epidermis and subcutaneous tissue. It is the thickest of the skin layers and comprises a tight, sturdy mesh of collagen and elastrin fibers. Both collagen and elastin are critically important skin proteins: collagen is responsible for the structural support and elastin for the resilience of the skin. The key type of cells in the dermis is fibroblasts, which synthesize collagen, elastin and other structural molecules. The proper function of fibroblasts is highly important for overall skin health. The dermis also contains capillaries (tiny blood vessels) and lymph nodes (depots of immune cells). The former are important for oxygenating and nourishing the skin, and the latter -- for protecting it from invading microorganisms. Finally, the dermis contains sebacious glands, sweat glands, hair follicles as well as a relatively small number of nerve and muscle sells. Sebacious glands, located around hair follicles, are of particular importance for skin health as they produce sebum, an oily protective substance that lubricates and waterproofs the skin and hair. When sebacious gland produce too little sebum, as is common in older people, the skin becomes excessively dry and more prone to wrinkling. Conversely, overproduction or improper composition of sebum, as is common in adolescents, often leads to acne. The dermis is the layer responsible for the skin's structural integrity, elasticity and resilience. Wrinkles arise and develop in the dermis. Therefore, an anti-wrinkle treatement has a chance to succeed only if it can reach as deep as the dermis. Typical collagen and elastin creams, for example, never reach the dermis because collagen and elastin molecules are too large to penetrate the epidermis. Hence, contrary to what some manufacturers of such creams might imply, these creams have little effect on skin wrinkles.
  • 12. Subcutaneous tissue Subcutanous (hypodermis) tissue is the innermost layer of the skin located under the dermis and consisting mainly of fat. The predominant type of cells in the subcutaneous tissue is adipocytes or fat cells. Subcutaneous fat acts as a shock absorber and heat insulator, protecting underlying tissues from cold and mechanical trauma. Interestingly, most mammals lack subcutaneous tissue because their fur serves as a shock absorber and heat insulator. Sweat glands and minute muscles attached to hair follicles originate in subcutaneous tissue. The loss of subcutaneous tissue, often occurring with age, leads to facial sag and accentuates wrinkles. A common procedure performed by dermatologists to counteract this process is to inject fat (collected elsewhere in the body) under the wrinkles on the face . DEFINITION:Basal cell carcinoma is the most common form of cancer worldwide and accounts for about 80% of all cases of skin cancer. CAUSES: In Book In Patient Radiation expose, UV Rays no Gene Maturations May be Arsenic exposure through ingestion no Immunosuppression May be Xerodermapigmentosum May be Epidermodysplasticverruciformis no Nevoid basal cell carcinoma syndrome No Bazex syndrome No Previous nonmelanoma skin cancer no Rombo syndrome No Alcohol consumption no
  • 13. Types of basal cell carcinoma of the skin In Book In My Patient Nodular: About 60% of BCCs are nodular. There is small nodes seen over the face. They start out as flat, well-defined lesions, then often become small bumps, which eventually collapse in the middle, leaving a raised ring on the border. Most nodular BCCs are on the face and so can be disfiguring if not treated promptly. Pigmented: Pigmented BCCs are similar to There is Black pigmentation seen over nodes the nodular type, but they can have brown or black spots in them. They can be confused with some types of melanoma. Fibrosing or Sclerotic: These BCCs are usually found on the face and look similar to scars. They are usually firm, ill-defined at the border, flat or slightly depressed, yellowish in color, and the surface tends to be smooth and shiny. Superficial: This type comprises about 15% of BCCs. They spread outward from a red, well-defined, scaly patch, most commonly found on the trunk and limbs. They are easily confused with psoriasis or eczema. Fibroepithelioma of Pinkus: This is a rare type of BCC. It tends to be a smooth, elevated, small nodule found on the back, extremities, groin, or sole of the foot. As those are not sun-exposed areas, this disease is probably not sun-related. PATHOPHYSIOLOGY: Over exposure to sun leads to the formation of thymine dimers, a form of DNA damage.
  • 14. cumulative DNA damage leading to mutations. Apart from the mutagenesis, over exposure to sunlight depresses the local immune system, Basal-cell carcinoma also develops as a result of Basal-Cell Nevus Syndrome, Developed tumors of the jaw, palmar or plantar (sole of the foot) pits, calcification of the falxcerebri (in the center line of the brain) and rib abnormalities. which inhibits the hedgehog signaling pathway. A mutation in the SMO gene, which is also on the hedgehog pathway, also causes basal-cell carcinoma CLINICAL MENIFESTATION: In Book In Patient Present skin bump or growth that is: Pearly or waxy White or light pink Flesh-colored or brown A skin sore that bleeds easily Present A sore that does not heal Present Oozing or crusting spots in a sore Not Present Appearance of a scar-like sore without Present having injured the area Irregular blood vessels in or around the Not Present spot A sore with a depressed (sunken) area in Not Present the middle ASSESSMENT & DIAGNOSTIC FINDINGS:
  • 15. IN BOOK IN PATIENT - Taking a thorough history - Done including family history - Physical examination (note BP - Done & weight) - Laboratory work (cholesterol - Done levels, glucose ) skin biopsy - Done Shave biopsy uses a thin surgical blade to shave off the top layers of skin. This is the most common method for diagnosing BCC. Punch biopsy uses a round, cookie cutter-like tool. It is used to take a deeper skin sample. MANAGEMENT: Curettage and electrodessication Surgical excision (removal) Mohs surgery (also known as "micrographic surgery"), especially if the lesion is on the face, is recurrent, has a diameter of greater than 2 cm, or is the sclerotic type Topical creams such as imiquimod is FDA-approved for the treatment of superficial BCCs not on the face, although studies have shown it can be effective against nodular BCC as well Excision Simple surgical excision (removal) is used to treat both primary and recurrent tumors. The procedure involves surgically removing the tumor and a certain amount of normal-appearing skin surrounding it (the "margin"): For basal cell and squamous cell carcinomas, margins are often 2 to 4 mm. The cure rates following excision are 95% and 92% for primary BCC and SCC, respectively, and are dependent on the site, size, and pattern of the tumor. Excision may be performed in the outpatient or inpatient setting depending on the extent of the cancer. Topical Creams Since its approval in 2004, the immune systemactivator imiquimod (also known by the brand nameAldara) has been a commonly prescribed topical (skin only) cream for small superficial and nodular basal cell carcinomas, as well as a pre-cancerous condition called actinic keratosis. It is spread on the lesion five times per week, usually for six weeks, and completely clears the skin in about 88% of patients or more, depending on the exact type of cancer. Another cream for superficial BCC is 5- flourouracil (Carac or Efudex), a chemotherapy drug that is also used intravenously. These treatments usually don't leave any scars, but they can cause considerable pain and swelling as they work. Several other creams are being tested now,
  • 16. including ingenolmebutate(PEP005), which is derived from a plant called the "petty spurge." Curettage and Electrodesiccation Curettage and electrodesiccationis a simple, quick and effective method for destroying small basal cell and squamous cell carcinomas. After scraping away the growth with a long spoon-like instrument called a curette, the physician uses a mild electric current to destroy any remaining abnormal cells. This scraping and cauterizing process is typically repeated three times, and the wound tends to heal without stitches. It is best for primary, not recurrent, lesions. The cure rates depend on the site: high-risk locations (nose, ear, chin, mouth) have a recurrence rate of 4% to 18%, depending on the tumor size. Recurrence rates decrease to 3% for tumors at low-risk sites of the trunk and extremities. Overall, the 5-year cure rates for primary BCC and SCC treated with C and E are 92% and 96%, respectively. Mohs Surgery TheMohs procedure (also known as Mohs micrographic surgery or margin controlled excision) is an advanced technique developed in the 1940s by Dr. Frederic E. Mohsfor removing lesions due to basal or squamous cell carcinoma. It involves removing thin sections of the skin growth, layer by layer. Each layer is then examined under the microscope, and removal of layers continues until no cancerous cells remain. It has the highest cure rate of any skin cancer treatment and doesn't cause as much scarring as other methods. It is especially useful for treating recurring skin cancer, larger tumors, tumors on the ear, eyelid, nose, lip, or hand, tumors in sites prone to recurrence, and the sclerotic subtype of basal cell carcinoma. It is the "gold standard" treatment: The 5-year recurrence rate is 1% for BCC and 3% for SCC. However, it is more costly, time-consuming, and labor-intensive than other methods. MEDICAL MANAGEMENT: - Chemotherapy in four cycle with Adreamycine andcyclophosphemide. - Analgesics - Antibiotics NURSING MANAGEMENT: - Identify at risk patients, & teach lifestyle modifications to prevent development any complication. - Teach patient to control cholesterol levels through dietary reduction of cholesterol intake, exercise, smoking cessation. - Note & report findings from history, physical examination, & laboratory results that indicate hypertension or diabetes, &teach to control blood pressure by taking treatment in the nearest hospital. NURSING DIAGNOSIS:
  • 17. 1. Risk for infection related to decrease immune system. 2. Altered body temperature due to presence of infection. 3. Imbalance nutritional level less than body requirement related to loss of appetite. 4. Activity intolerance related to disease. 5 Impaired body image due disease. 6 Altered self image and confidence due to fegure.  HEALTH TEACHING: Explain patient’s relatives about discharge planning. Give advice about regular medication as per timing. Advice given about good nutritive diet. Advice given for prevention of infection management. Prevention The best way to prevent skin cancer is to reduce your exposure to sunlight. Ultraviolet light is most intense at midday, so try to avoid sun exposure during these hours. Protect the skin by wearing hats, long-sleeved shirts, long skirts, or pants. Always use sunscreen: Apply high-quality sunscreens with SPF (sun protection factor) ratings of at least 15. Look for sunscreens that block both UVA and UVB light. Apply sunscreen at least 30 minutes before going outside, and reapply it frequently. Use sunscreen in winter, too. Possible Complications Untreated, basal cell cancer can spread to nearby tissues or structures, causing damage. This is most worrisome around the nose, eyes, and ears. Explain about follow up care.
  • 18. BIBLIOGRAPHY: 1. Bennette and Plum; “TEXTBOOK OF MEDITION ; 10thedition, 1996; W.B. Saunders Company, New York : 1996. PP : 2. Black J.M; “MEDICAL SURGICAL NURSING; 5th edition, 1999 ; W.B. Saunders Company, Philadelphia. PP: 3. Brunners&Suddarth’s; “TEXT BOOK OF MEDICAL SURGICAL NURSING VOL-_1”;10th edition, 2004; Elsevier Publishers, New Delhi, India. PP: 4. B T Basavanthappa;”TEXT BOOK OF NURSING THEORIES”,Jaypee brothers Medical Publishers ,New Delhi. PP: 40- WEBSITES: - http://www.wikipedia.com. - http://www.patho.skindisease.org/.com.in - http://www.google.com. - http://www.medicine.com.